
Keywords: TNFR، گیرنده فاکتور نکروز تومور; IL4, interleukin 4; IMQ, imiquimod; PASI, psoriasis area severity index; TNFR, tumor necrosis factor receptor; TLR7/8, toll-like receptor 7/8; SIP, small immune proteinPsoriasis; Chronic skin inflammation; Interleukin 4; Antibody-cytokine fusion protein;