دانلود مقالات ISI درباره Topoisomerase Ii + ترجمه فارسی

A novel tetrahydrobenzoangelicin with dark and photo biological activity

Keywords: Tetrahydrobenzoangelicin; Antiproliferative activity; Photobiological activity; DNA interaction; Topoisomerase II;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

The DNA topoisomerase II catalytic inhibitor merbarone is genotoxic and induces endoreduplication

Keywords: Topoisomerase II; Catalytic inhibitor; Merbarone; DNA damage; Clastogens; Endoreduplication;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Mitotic chromosome condensation in vertebrates

Keywords: Chromosomes; Condensation; Condensin; Cohesin; Topoisomerase II; Histones

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Chemical reactivity and microbicidal action of bethoxazin

Keywords: Cys; cysteine; DTT; dithiotreitol; ESI; electrospray ionization; GSH; glutathione; HRMS; high resolution mass spectrometry; HSA; human serum albumin; kDNA; kinetoplast plasmid DNA; kobs; pseudo first order rate constant; LC; liquid chromatography; MS; mas

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Synthesis and identification of novel indolo[2,3-a]pyrimido[5,4-c]carbazoles as a new class of anti-cancer agents

Keywords: Indolocarbazoles; Azaindolocarbazoles; Bisindolylmaleimides; Pyrimidines; Photocyclisation; Anti-cancer; Topoisomerase II

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

The anticancer multi-kinase inhibitor dovitinib also targets topoisomerase I and topoisomerase II

Keywords: Dovitinib; Anticancer; DNA; Topoisomerase II; Topoisomerase I;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Dihydroxylated 2,4,6-triphenyl pyridines: Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship study

Keywords: Dihydroxylated 2,4,6-triphenyl pyridines; Topoisomerase I; Topoisomerase II; Cytotoxicity; Anticancer agents

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Anti-cancer activity and mutagenic potential of novel copper(II) quinolinone Schiff base complexes in hepatocarcinoma cells

Keywords: Quinolinones; Hepatocellular carcinoma; Mutagenicity; Topoisomerase II; Copper(II);

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

First synthesis and anticancer activity of novel naphthoquinone amides

Keywords: Anticancer activity; Cancer; Naphthoquinone amides; Structure activity relationships; Topoisomerase II

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2012 سفارش ترجمه

Synthesis and topoisomerase II inhibitory and cytotoxic activity of oxiranylmethoxy- and thiiranylmethoxy-chalcone derivatives

Keywords: Chalcone; Retrochalcone; Topoisomerase II; Anticancer agents; Oxiranylmethoxy-chalcone; Thiiranylmethoxy-chalcone;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Synthesis of 4β-carbamoyl epipodophyllotoxins as potential antitumour agents

Keywords: Podophyllotoxin; Epipodophyllotoxin; Carbamate; Topoisomerase II; Cytotoxicity

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Cadmium is a catalytic inhibitor of DNA topoisomerase II

Keywords: Cadmium; Topoisomerase II; DNA; Cytotoxicity; Decatenation;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Synthesis and evaluation of aroylthiourea derivatives of 4-β-amino-4'-O-demethyl-4-desoxypodophyllotoxin as novel topoisomerase II inhibitors

Keywords: 4-β-Amino-4′-O-demethyl-4-desoxypodophyllotoxin; Aroylthiourea; Anticancer agents; Topoisomerase II;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Cationic nanoemulsion as a delivery system for oligonucleotides targeting malarial topoisomerase II

Keywords: Oligonucleotides; Cationic nanoemulsion; DOTAP; Topoisomerase II; Plasmodium falciparum

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Predictive value of multidrug resistance proteins, topoisomerases II and ERCC1 in small cell lung cancer: A systematic review

Keywords: Small-cell lung cancer; Predictive factor; Multidrug resistance-associated proteins; MDR1; MRP; MVP; Topoisomerase II; ERCC1;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Inhibitors of mTOR overcome drug resistance from topoisomerase II inhibitors in solid tumors

Keywords: mTOR; DNA damage; Chemotherapeutic drugs; G2/M arrest; Topoisomerase II; γH2AX

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Synthesis and characterization of mixed-ligand diimine-piperonal thiosemicarbazone complexes of ruthenium(II): Biophysical investigations and biological evaluation as anticancer and antibacterial agents

Keywords: Thiosemicarbazone; Diimine; DNA; Anticancer; Human serum albumin; Topoisomerase II

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Synthesis and evaluation of mansonone F derivatives as topoisomerase inhibitors

Keywords: Synthesis; Mansonone F derivatives; Cytotoxic activity; Topoisomerase I; Topoisomerase II

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Half-sandwich ruthenium–arene complexes with thiosemicarbazones: Synthesis and biological evaluation of [(η6-p-cymene)Ru(piperonal thiosemicarbazones)Cl]Cl complexes

Keywords: Topoisomerase II; Human serum albumin; Thiosemicarbazone; Organometallic ruthenium; Anticancer; Antibacterial

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Acrylamide catalytically inhibits topoisomerase II in V79 cells

Keywords: Acrylamide; Topoisomerase II; V79 cells

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

A murine experimental anthracycline extravasation model: Pathology and study of the involvement of topoisomerase II alpha and iron in the mechanism of tissue damage

Keywords: Anthracycline extravasation; Dexrazoxane; Pathology; Toxicity mechanism; Topoisomerase II; Iron chelation

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Resveratrol induces DNA double-strand breaks through human topoisomerase II interaction

Keywords: RSV, resveratrol; TOPO II, topoisomerase II; DSBs, double-strand breaksγH2AX; Cell cycle; Topoisomerase II; Double-strand breaks; Cytofluorimetric assay

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Pyridazinopsoralens of wide chemotherapeutic interest

Keywords: Pyridazinopsoralens; Photobiological evaluation; Antiproliferative activity; Topoisomerase II;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

The role of the DNA hypermethylating agent Budesonide in the decatenating activity of DNA topoisomerase II

Keywords: Topoisomerase II; Hypermethylation of DNA; Chromosome segregation; Endoreduplication

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Effect of the anti-neoplastic drug doxorubicin on XPD-mutated DNA repair-deficient human cells

Keywords: Nucleotide excision repair; Doxorubicin; Xeroderma pigmentosum group D; Topoisomerase II; Cancer

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Targeting the ICB2 site of the topoisomerase IIα promoter with a formamido-pyrrole-imidazole-pyrrole H-pin polyamide

Keywords: Polyamides; DNA; Topoisomerase II; Sequence specificity; Minor groove binders; NF-Y; Gene expression;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

A diazirine-based photoaffinity etoposide probe for labeling topoisomerase II

Keywords: Photoaffinity labeling; Etoposide; Topoisomerase II; Diazirine

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Topoisomerase II inhibition by the bioactivated benzene metabolite hydroquinone involves multiple mechanisms

Keywords: Benzene; Topoisomerase II; Leukemia; Mechanism of action

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Design, synthesis and biological evaluation of a novel series of anthrapyrazoles linked with netropsin-like oligopyrrole carboxamides as anticancer agents

Keywords: Netropsin; DNA; Minor groove; Intercalator; Anthrapyrazole; Anticancer; Topoisomerase I; Topoisomerase II; Cytotoxic

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Increased cytotoxicity of an unusual DNA topoisomerase II inhibitor compound C-1305 toward HeLa cells with downregulated PARP-1 activity results from re-activation of the p53 pathway and modulation of mitotic checkpoints

Keywords: MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; DAPI, 4′,6-diamidino-2-phenyindole diacetate; NU1025, 8-hydroxy-2-methylquinazoline-4-one; m-AMSA, 4’-(9-acridinylamino)methanesulfon-m-anisididePARP-1; Topoisomerase II; Combination thera

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Topoisomerase IIα-dependent induction of a persistent DNA damage response in response to transient etoposide exposure

Keywords: Topoisomerase II; Etoposide; Double-stranded DNA breaks; Non-homologous end joiningDSB, double-stranded DNA breaks; TopoII, topoisomerase II; CC, cleavage complex; NHEJ, non-homologous DNA end joining; DNA-PKcs, DNA-dependent protein kinase catalytic subu

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2010 سفارش ترجمه

Topoisomerase IIα inhibition following DNA transfection greatly enhances random integration in a human pre-B lymphocyte cell line

Keywords: Topoisomerase II; Random integration; Gene targeting; Nalm-6

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

The mycotoxin ochratoxin A inhibits DNA topoisomerase II and induces polyploidy in cultured CHO cells

Keywords: Ochratoxin A; Cytotoxicity; DNA damage; Topoisomerase II; Polyploidy

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Evidence for the presence of R250G mutation at the ATPase domain of topoisomerase II in an arsenite-resistant Leishmania donovani exhibiting a differential drug inhibition profile

Keywords: Leishmania donovani; Topoisomerase II; Novobiocin; Pentamidine; Doxorubicin; Actinomycin D

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

The structure-based design, synthesis, and biological evaluation of DNA-binding amide linked bisintercalating bisanthrapyrazole anticancer compounds

Keywords: Bisanthrapyrazole; Bisintercalating; DNA-binding; Topoisomerase II

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

DNA-targeting pyrroloquinoline-linked butenone and chalcones: Synthesis and biological evaluation

Keywords: Pyrroloquinoline; Chalcones; Antiproliferative activity; Topoisomerase II

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Assessment of DNA double-strand breaks and γH2AX induced by the topoisomerase II poisons etoposide and mitoxantrone

Keywords: DNA double-strand breaks; Topoisomerase II; Etoposide; Mitoxantrone; Neutral comet assay; γH2AX; Genotoxicity thresholds

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Topoisomerase IIα gene status and prediction of pathological complete remission after anthracycline-based neoadjuvant chemotherapy in endocrine non-responsive Her2/neu-positive breast cancer

Keywords: Predictive markers; Topoisomerase II; Preoperative chemotherapy; Breast cancer

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Synthesis of 1-/2-substituted-[1,2,3]triazolo[4,5-g]phthalazine-4,9-diones and evaluation of their cytotoxicity and topoisomerase II inhibition

Keywords: Triazolophthalazine; Cytotoxicity; Topoisomerase II

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

The effects of 1,4-benzoquinone on c-Myb and topoisomerase II in K-562 cells

Keywords: Benzoquinone; c-Myb; Topoisomerase II; K-562 cells;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

The high rate of endoreduplication in the repair deficient CHO mutant EM9 parallels a reduced level of methylated deoxycytidine in DNA

Keywords: Topoisomerase II; Hypomethylation of DNA; Chromosome segregation; Endoreduplication

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

The regulation of sister chromatid cohesion

Keywords: Cohesin; Chromosome segregation; Topoisomerase II; Mouse models

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Synthesis and biological evaluation of pyrroloiminoquinone derivatives

Keywords: Pyrroloiminoquinone derivatives; Antiproliferative activity; Topoisomerase II; DNA fragmentation

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

The structure-based design, synthesis and biological evaluation of DNA-binding bisintercalating bisanthrapyrazole anticancer compounds

Keywords: Bisanthrapyrazole; Bisintercalating; Anticancer; DNA-binding; Topoisomerase II; DNA; Molecular modeling; Docking; Cytotoxicity; K562 cells; Cardiotoxic

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

NK314, a novel topoisomerase II inhibitor, induces rapid DNA double-strand breaks and exhibits superior antitumor effects against tumors resistant to other topoisomerase II inhibitors

Keywords: NK314; DNA double-strand breaks; Topoisomerase II; Etoposide

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

Cell cycle-dependent DNA damage signaling induced by ICRF-193 involves ATM, ATR, CHK2, and BRCA1

Keywords: DNA damage; ICRF-193; Topoisomerase II; Cell cycle; G2 arrestA-T, ataxia-telangiectasia; ATM, ataxia-telangiectasia mutated; ATR, ATM- and Rad3-related; DSB, DNA double-strand breaks; IR, ionizing radiation; ATR-kd, kinase-dead ATR; LMP, low melting point

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2008 سفارش ترجمه

3,5-Bis(3′-indolyl)pyrazoles, analogues of marine alkaloid nortopsentin: Synthesis and antitumor properties

Keywords: Nortopsentins; 3,5-Bis(3′-indolyl)pyrazoles; Antitumor activity; Topoisomerase II

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2007 سفارش ترجمه

Synthetic approach to condensed heterocyclic analogues from etoposide revisited. Synthesis of A-ring pyridazine etoposide

Keywords: Anticancer drugs; Etoposide; Topoisomerase II; Stille reaction;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2007 سفارش ترجمه

Analogs of the marine alkaloid makaluvamines: Synthesis, topoisomerase II inhibition, and anticancer activity

Keywords: Makaluvamine; Analog; HCT-116; MCF-7; MDA-MB-468; Topoisomerase II

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2007 سفارش ترجمه

Point mutations in mitochondrial topoisomerase enzymes of Trypanosoma congolense are not involved in isometamidium resistance

Keywords: Trypanosoma congolense; Drug resistance; Isometamidium; Topoisomerase II;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2007 سفارش ترجمه