Keywords: DNA topology; Topoisomerases; Topology simplification;
مقالات ISI (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Synthesis, DNA interaction, topoisomerase I, II inhibitory and cytotoxic effects of water soluble silicon (IV) phthalocyanine and napthalocyanines bearing 1-acetylpiperazine units
Keywords: Synthesis; Silicon; Water solubility; Cytotoxicity; DNA cleavage; Topoisomerases;
Probing the evolutionary conserved residues Y204, F259, S400 and W590 that shape the catalytic groove of human TDP1 for 3â²- and 5â²-phosphodiester-DNA bond cleavage
Keywords: hTDP1; human tyrosyl-DNA phosphodiesterase 1; TOP1; topoisomerase I; TOP2; topoisomerase II; TOP1cc; TOP1 cleavage complex; TOP2cc; TOP2 cleavage complex; DNA damage and repair; 3â²-End blocking DNA lesions; 5â²-End blocking DNA lesions; Topoisomerases;
Design, synthesis and antibacterial properties of pyrimido[4,5-b]indol-8-amine inhibitors of DNA gyrase
Keywords: ESKAPE pathogens; Anti-infectives; Topoisomerases; DNA gyrase; Pyrimido[4,5-b]indol-8-amine;
Novel indolizino[8,7-b]indole hybrids as anti-small cell lung cancer agents: Regioselective modulation of topoisomerase II inhibitory and DNA crosslinking activities
Keywords: Anti-SCLC hybrids; β-carboline; bis(hydroxymethyl)pyrrole; indolizino[8,7-b]indole; DNA cross-linking; Topoisomerase inhibition; Ac2O; acetic anhydride; ACN; acetonitrile; CCRF-CEM; human lymphoblastic leukemia; CCRF-CEM/VBL; vinblastine-resistant CCRF-C
Synthesis biological screening and molecular docking studies of some tin (IV) Schiff base adducts
Keywords: Schiff base; Organotin; Topoisomerases; Cisplatin; Antitumor activity;
Discovery and structure-activity relationships of a novel isothiazolone class of bacterial type II topoisomerase inhibitors
Keywords: ESKAPE pathogens; Anti-infectives; Topoisomerases; DNA gyrase; Isothiazolone;
Mutations reducing replication from R-loops suppress the defects of growth, chromosome segregation and DNA supercoiling in cells lacking topoisomerase I and RNase HI activity
Keywords: Topoisomerases; Supercoiling; Replication; RNase HI; R-loops; Gyrase;
TOP2A gene copy gain predicts response of epithelial ovarian cancers to pegylated liposomal doxorubicin ★: TOP2A as marker of response to PLD in ovarian cancer
Keywords: Topoisomerases; Predictive biomarkers; Doxorubicin; PDX (patient derived xenografts)
Lanostane-type triterpenoids from Abies faxoniana and their DNA topoisomerase inhibitory activities
Keywords: Abies faxoniana; Pinaceae; Triterpenoids; Topoisomerases;
Identification of novel PARP inhibitors using a cell-based TDP1 inhibitory assay in a quantitative high-throughput screening platform
Keywords: TDP1; PARP; Topoisomerases; Drug discovery; Combination therapy
Epigenetic and genetic inactivation of tyrosyl-DNA-phosphodiesterase 1 (TDP1) in human lung cancer cells from the NCI-60 panel
Keywords: TDP1; Topoisomerases; Topotecan; CellMiner; Promoter hypermethylation
Tyrosyl-DNA-phosphodiesterases (TDP1 and TDP2)
Keywords: Topoisomerases; Poly(ADPribose) polymerases (PARP); Homologous Recombination (HR); Non-homologous end joining (NHEJ); Chemotherapy;
Novel synthetic 9-benzyloxyacridine analogue as both tyrosine kinase and topoisomerase I inhibitor
Keywords: Acridine; Topoisomerases; Tyrosine kinases; Antitumor; DNA-binding
Synthesis, cytotoxicity and topoisomerase inhibition properties of multifarious aminoalkylated indeno[1,2-c]isoquinolin-5,11-diones
Keywords: Cancer; DNA intercalators; Topoisomerases; Indenoisoquinolines
Indeno[1,2-c]isoquinolin-5,11-diones conjugated to amino acids: Synthesis, cytotoxicity, DNA interaction, and topoisomerase II inhibition properties
Keywords: Cancer; DNA ligand; Topoisomerases; Cytotoxicity; Amino acid conjugate; Indenoisoquinolin-5,11-dione
Analysis of topoisomerase mutations in fluoroquinolone-resistant and -susceptible Campylobacter jejuni strains isolated in Senegal
Keywords: Campylobacter jejuni; Fluoroquinolones; Resistance; Topoisomerases; Mutation; Senegal
In vitro activity of garenoxacin tested against a worldwide collection of ciprofloxacin-susceptible and ciprofloxacin-resistant Enterobacteriaceae strains (1999–2004)
Keywords: Garenoxacin; Fluoroquinolones; Enterobacteriaceae; CLSI; Resistance; Topoisomerases
Role of DNA topoisomerase IIβ in neurite outgrowth
Keywords: CHX, cycloheximide; DRB, 5,6-dichloro-1-beta-ribofuranosyl-benzimidazole; ICRF-193, Imperial Cancer Research Fund-193; NGF, nerve growth factorNeurons; Differentiation; Neurite outgrowth; Topoisomerases; Gene regulation
Origin and evolution of DNA topoisomerases
Keywords: Topoisomerases; EvolutionTopo, topoisomerase; HGT, horizontal gene transfer; BV, bootstrap value; CTD, C-terminal domain; LUCA, last universal common ancestor