Keywords: توپوتان; 2,5-DXP; 2,5-diketopiperazine; ACC; adenoid cystic carcinomas; BBR; berberine; BET; bromodomain and extraterminal; CA; chebulagic acid; CPT; camptothecin; EMT; epithelial-mesenchymal transition; GSK3; glycogen synthase kinase 3-; HCC; hepatocellular carci
مقالات ISI توپوتان (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: توپوتان; Doxorubicin; Topotecan; Nitrogen doped reduced graphene; 1-methyl-3-octylimidazolium chloride; Electrochemical sensor;
Keywords: توپوتان; Blood-retinal barrier; Retinoblastoma; Topotecan; Pantoprazole; Microdialysis; Rabbit; ABC transporters; BCRP; ABCG2/BCRP; P-gp; ABCB1/P-gp; Pediatric cancer; Vitreous; Retina; Distribution; Delivery; Xenograft;
Keywords: توپوتان; Nanosuspension; Safety; Nanotoxicology; Sterilization; Drug delivery; NCEs; new chemical entities; MTD; maximum tolerated doses; IV; intravenous; MPS; mononuclear phagocyte system; EPR; enhanced permeability and retention; HPMC; hydroxy propyl methyl cell
Keywords: توپوتان; Cervical cancer; Topotecan; Solid lipid nanoparticles; Chemotherapy;
Keywords: توپوتان; hydroxycamptothecin; folate-decorated human serum albumin; targeted delivery system; tissue distribution; CPT; camptothecin; DMEM; Dulbecco's modified eagle medium; FA; folate; FA-HSA-nHCPT-NPs; folate-decorated human serum albumin loaded with nano-hydrox
Keywords: توپوتان; Release kinetics; Topotecan; Liposomes; Fluorescence spectroscopy; Nanotechnology;
Keywords: توپوتان; Small cell lung cancer; Hyponatremia; Topotecan; Prognostic; Second-line; Serum sodium (Napl);
Keywords: توپوتان; SCLC; Topotecan; Sensitive relapse; Resistant relapse
Keywords: توپوتان; Bevacizumab; ISG15 expression; Non-small-cell lung cancer; Refractory; Second-line therapy; Topotecan;
Keywords: توپوتان; Amrubicin; Randomized trial; Small cell lung cancer; TAS-102; Topotecan
Keywords: توپوتان; Topotecan; Hydrogels; Cytotoxicity; Retinoblastoma; Rabbits
Topotecan alleviates ventilator-induced lung injury via NF-κB pathway inhibition
Keywords: توپوتان; Ventilator-induced lung injury; Topotecan; Nuclear factor-kappa B (NF-κB);
Image-guided thermosensitive liposomes for focused ultrasound drug delivery: Using NIRF-labelled lipids and topotecan to visualise the effects of hyperthermia in tumours
Keywords: توپوتان; Near infrared fluorescence; MRI; Imaging; Focused ultrasound; Liposomes; Topotecan; Localised drug delivery; Cancer;
A novel nanocomposite based on gold nanoparticles loaded on acetylene black for electrochemical sensing of the anticancer drug topotecan in the presence of high concentration of uric acid
Keywords: توپوتان; Topotecan; Acetylene black; Gold nanoparticles; Modified electrode; Voltammetric nanosensor; Drug analysis;
Comparison of DSB effects of the beta particles of iodine-131 and 6Â MV X-ray at a dose of 2Â Gy in the presence of 2-Methoxyestradiol, IUdR, and TPT in glioblastoma spheroids
Keywords: توپوتان; DSB damage; Glioblastoma; IUdR; 2-Methoxyestradiol; Topotecan;
The combination of A-966492 and Topotecan for effective radiosensitization on glioblastoma spheroids
Keywords: توپوتان; Glioblastoma; PARP inhibitor; Topoisomerase I inhibitor; Topotecan; Radiosensitivity;
Modulating angiogenesis with integrin-targeted nanomedicines
Keywords: توپوتان; (RGD)m; RGD mimetics; 4-NQO; 4-nitroquinoline 1-oxide; AAA; Abdominal Aortic Aneurysms; ADA; 8-Amino-3,6-Dioxaoctonoic Acid; AH-GDM; Aminohexyl-Geldanamycin; ami; Amide; AP-2α; Activating Protein 2α; ARMS; Alveolar Rhabdomyosarcoma; ATO; Arsenic Trioxid
Synergistic enhancement of topotecan-induced cell death by ascorbic acid in human breast MCF-7 tumor cells
Keywords: توپوتان; TPT; Topotecan; AA; Ascorbic Acid; Topo; Topoisomerase; ESR; Electron Spin Resonance; HRP; Horseradish Peroxidase; GSH; Reduced Glutathione; GSSG; Oxidized Glutathione; DMPO; 5,5-Dimethyl Pyrroline-1-N-oxide; ROS; Reactive Oxygen Species; Topotecan; Ascor
Halogenated naphthochalcones and structurally related naphthopyrazolines with antitumor activity
Keywords: توپوتان; ABC; adenosine triphosphate binding cassette; BCRP; breast cancer resistance protein; FTC; fumitremorgin C; MDR; multidrug resistance; P-gp; P-glycoptotein; SD; standard deviation; TdT; Terminal deoxyribonucleotide Transferase; Topo; topotecan; TUNEL; Ter
Intracellular uptake study of radiolabeled anticancer drug and impedimetric detection of its interaction with DNA
Keywords: توپوتان; 131I; Small cell lung cancer; Impedimetric Detection; Drug-DNA interaction; Topotecan;
Probing the binding of anticancer drug topotecan with human hemoglobin: Structural and thermodynamic studies
Keywords: توپوتان; Hemoglobin; Topotecan; Spectroscopy; Calorimetry; Interaction;
Cytoskeletal interference – A new mode of action for the anticancer drugs camptothecin and topotecan
Keywords: توپوتان; Camptothecin (PubChem CID: 24360); Topotecan (PubChem CID: 60700); Colchicine (PubChem CID: 6167); Vinblastine (PubChem CID: 13342); Latrunculin B (PubChem CID: 6436219)Camptothecin; Topotecan; DNA topoisomerase; Microtubule; Actin filament
DNA-Topoisomerase I, a new target for the treatment of neuroblastoma
Keywords: توپوتان; topoisomerase I; irinotecan; topotecan; neuroblastoma; xenografts
Binding of topotecan to chromatin: Insights into cooperative binding and comparison with DNA
Keywords: توپوتان; Genotoxicity; Topotecan; Chromatin; Histones; Spectroscopy;
Effect of poly(ADP-ribose)polymerase and DNA topoisomerase I inhibitors on the p53/p63-dependent survival of carcinoma cells
Keywords: توپوتان; Apoptosis; Carcinoma cells; p53/p63 targets; PJ34; Topotecan
Electrochemical investigation of the interaction between topotecan and DNA at disposable graphite electrodes
Keywords: توپوتان; Topotecan; Drug–DNA interactions; Pencil graphite electrode; Single walled carbon nanotubes; Differential pulse voltammetry; Electrochemical impedance spectroscopy
Cabazitaxel Versus Topotecan in Patients with Small-Cell Lung Cancer with Progressive Disease During or After First-Line Platinum-Based Chemotherapy
Keywords: توپوتان; Cabazitaxel; Phase 2; Small-cell lung cancer; Relapse; Topotecan;
Phase II study of temozolomide in combination with topotecan (TOTEM) in relapsed or refractory neuroblastoma: A European Innovative Therapies for Children with Cancer-SIOP-European Neuroblastoma study
Keywords: توپوتان; Paediatrics; Temozolomide; Topotecan; Phase II; Neuroblastoma;
Epigenetic and genetic inactivation of tyrosyl-DNA-phosphodiesterase 1 (TDP1) in human lung cancer cells from the NCI-60 panel
Keywords: توپوتان; TDP1; Topoisomerases; Topotecan; CellMiner; Promoter hypermethylation
The role of pH and ring-opening hydrolysis kinetics on liposomal release of topotecan
Keywords: توپوتان; Liposomes; Nanotechnology; Topotecan; Kinetics; Membrane binding; Permeability;
Topotecan-tamoxifen duple PLGA polymeric nanoparticles: Investigation of in vitro, in vivo and cellular uptake potential
Keywords: توپوتان; Topotecan hydrochloride (PubChem CID: 60699); Tamoxifen citrate (PubChem CID: 2733525); PLGA (PubChem CID: 23111554); Poly vinyl alcohol (PubChem CID: 23111554); Mannitol (PubChem CID: 6251; Dichloromethane (PubChem CID: 6251); EDTA (PubChem CID: 6049); D
Synthesis, antiproliferative and anti-dengue virus evaluations of 2-aroyl-3-arylquinoline derivatives
Keywords: توپوتان; 2-Aroyl-3-arylquinoline; Ribavirin; Topotecan; Anti-dengue virus; Antiproliferative
PK/TD modeling for prediction of the effects of 8C2, an anti-topotecan mAb, on topotecan-induced toxicity in mice
Keywords: توپوتان; Pharmacokinetic/toxicodynamic model; Monoclonal antibody; Subcutaneous bioavailability; Topotecan; 8C2; Intraperitoneal chemotherapy; Inverse targeting; Surface plasmon resonance; Enzyme linked immunosorbent assay; Immunotoxicotherapy;
DJ-1 mediates the resistance of cancer cells to dihydroartemisinin through reactive oxygen species removal
Keywords: توپوتان; ARTs; artemisinin and its derivatives; BCRP; breast cancer resistance protein; DCF-DA; 2â²,7â²-dichlorodihydrofluorescein diacetate; DHA; dihydroartemisinin; DHE; dihydroethidine; 5-FU; 5-fluorouracil; GCLC; glutamate-cysteine ligase catalytic subunit
Absolute bioavailability studies of a new oral topotecan formulation in Chinese patients using UHPLC-MS/MS
Keywords: توپوتان; Topotecan; Bioavailability; Pharmacokinetics; Small cell lung cancer (SCLC); UHPLC-MS/MS;
Multicenter phase II trial of topotecan, cisplatin and bevacizumab for recurrent or persistent cervical cancer
Keywords: توپوتان; Cervical cancer; Chemotherapy; Topotecan; Cisplatin; Bevacizumab; PET/CT;
ATM is required for the repair of Topotecan-induced replication-associated double-strand breaks
Keywords: توپوتان; ATM; Topotecan; Homology-directed repair; Replication-associated DSBs; SKX;
Sildenafil is not a useful modulator of ABCB1 and ABCG2 mediated drug resistance in vivo
Keywords: توپوتان; Multidrug resistance; P-glycoprotein; BCRP protein; Brain penetration; Sildenafil; Docetaxel; Topotecan; Doxorubicin;
The human topoisomerase 1B Arg634Ala mutation results in camptothecin resistance and loss of inter-domain motion correlation
Keywords: توپوتان; hTop1B; human topoisomerase 1B; CPT; camptothecin; TPT; topotecan; DMSO; dimethyl sulfoxide; EDTA; ethylenediaminetetraacetic acid; EGTA; ethylene glycol tetraacetic acid; DTT; dithiothreitol; BSA; bovine serine albumin; TBE; tris-borate-EDTA; PMSF; pheny
Ocular and systemic toxicity of intravitreal topotecan in rabbits for potential treatment of retinoblastoma
Keywords: توپوتان; intravitreal; topotecan; rabbits; retinoblastoma
Weekly topotecan and cisplatin (TOPOCIS) as neo-adjuvant chemotherapy for locally-advanced squamous cervical carcinoma: Results of a phase II multicentric study
Keywords: توپوتان; Cervical cancer; Neoadjuvant therapy; Topotecan; Cisplatin; Treatment efficacy; Treatment toxicity
Sensitive method for plasma and tumor Ko143 quantification using reversed-phase high-performance liquid chromatography and fluorescence detection
Keywords: توپوتان; Ko143; Fumitremorgin C; Roquefortine C; Topotecan; ABCG2; Drug resistance
Prolongation of time interval between doses could eliminate accelerated blood clearance phenomenon induced by pegylated liposomal topotecan
Keywords: توپوتان; Pegylated liposomes; Repeated injection; Accelerated blood clearance; Time interval; Topotecan
Spectroscopy and dynamics of topotecan anti-cancer drug comprised within cyclodextrins
Keywords: توپوتان; Anticancer drug; Topotecan; Cyclodextrin; Spectroscopy; Inclusion complexes; Proton-transfer dynamics
A phase I study of concurrent weekly topotecan and cisplatin chemotherapy with whole pelvic radiation therapy in locally advanced cervical cancer: A gynecologic oncology group study
Keywords: توپوتان; Cervical cancer; Topotecan; Cisplatin; Pelvic radiation
Repeated injections of PEGylated liposomal topotecan induces accelerated blood clearance phenomenon in rats
Keywords: توپوتان; Polyethylene glycol (PEG); Accelerate blood clearance (ABC) phenomenon; PEGylated liposomes; Topotecan
Topotecan exposure estimation in pediatric acute myeloid leukemia supported by LC-MS-based drug monitoring and pharmacokinetic analysis
Keywords: توپوتان; Topotecan; Acute myeloid leukemia (AML); Pediatrics; Liquid chromatography coupled to mass spectrometry (LC-MS); Pharmacokinetic analysis;
Topotecan/Cisplatin Compared with Cisplatin/Etoposide as First-Line Treatment for Patients with Extensive Disease Small-Cell Lung Cancer: Final Results of a Randomized Phase III Trial
Keywords: توپوتان; Small-cell lung cancer; First-line chemotherapy; Topotecan
A novel method to load topotecan into liposomes driven by a transmembrane NH4EDTA gradient
Keywords: توپوتان; Liposomes; Topotecan; NH4EDTA; Antitumor efficacy; Toxicity