
Negative inotropic effects of epinephrine in the presence of increased β-adrenoceptor sensitivity during hypothermia in a rat model
Keywords: LV, left ventricle; CO, cardiac output; SV, stroke volume; cAMP, cyclic adenosine monophosphate; TPR, total peripheral resistance; PDE3, phosphodiesterase 3; IC50, the half maximal inhibitory concentration; Gp, parallel conductance; MAP, mean arterial pre