Mapping the UDP-N-acetylglucosamine regulatory site of human glucosamine-6P synthase by saturation-transfer difference NMR and site-directed mutagenesis
Keywords: Glucosamine-6-phosphate synthase; UDPGlcNAc binding site; Glutamine amidotransferase; STD-NMR; Allosteric regulation; Transferred NOE; Fru6P; d-fructose-6-phosphate; Glc6P; d-glucose-6-phosphate; GlcN6P; d-glucosamine-6-phosphate; hGfat; human l-glutamine