Discovery and antiplatelet activity of a selective PI3Kβ inhibitor (MIPS-9922)
Keywords: PI3 kinase; Kinase selectivity; Platelet aggregation inhibitors; ThrombosisACD, Acid citrate dextrose; PTEN, phosphatase and tensin homolog; ADME, absorption, distribution, metabolism, and excretion; TRAP, thrombin receptor activating peptide; PRP, platel