ReviewClonal cooperativity in heterogenous cancers
Keywords: تومور ناهمگونی; Tumor heterogeneity; Clonal cooperativity; Epithelial to mesenchymal transition; Metastasis;
مقالات ISI تومور ناهمگونی (ترجمه نشده)
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Primary Double-Strike Therapy for Cancers to Overcome EGFR Kinase Inhibitor Resistance: Proposal from the Bench
Keywords: تومور ناهمگونی; EGFR mutation; Acquired resistance; Molecular mechanisms; Drug-tolerant state; Microenvironment; Tumor heterogeneity;
CRISPR/Cas9 editing of the genome for cancer modeling
Keywords: تومور ناهمگونی; CRISPR/Cas9; Cancer model; Tumor suppressor; Oncogene; Tumor heterogeneity; CRISPR-barcoding;
Nano-sized metabolic precursors for heterogeneous tumor-targeting strategy using bioorthogonal click chemistry in vivo
Keywords: تومور ناهمگونی; Click chemistry; Polymerized metabolic precursors; Tumor heterogeneity; Metabolic glycoengineering; Tumor targeting;
Integration of PET/MR Hybrid Imaging into Radiation Therapy Treatment
Keywords: تومور ناهمگونی; Hybrid PET/MR imaging; Radiation therapy; PET tracers; Tumor response; Normal tissue toxicity; Tumor heterogeneity; MRI-based treatment planning;
Summary of the 2016 American Association for Cancer Research (AACR) Annual Meeting
Keywords: تومور ناهمگونی; Immunotherapy; Chemoresistance; Tumor heterogeneity; Personalized therapy; Preclinical models; Moonshot;
Changes of heterogeneous cell populations in the Ishikawa cell line during long-term culture: Proposal for an in vitro clonal evolution model of tumor cells
Keywords: تومور ناهمگونی; Genome instability; Cell culture passage; Cell line authentication; Tumor heterogeneity; Chromosome rearrangements;
PET-Based Molecular Imaging in Designing Personalized Management Strategy in Gastroenteropancreatic Neuroendocrine Tumors
Keywords: تومور ناهمگونی; Neuroendocrine tumor; Personalized management; Somatostatin receptor imaging; FDG-PET/CT; Tumor biology; Tumor heterogeneity; Molecular imaging;
Serum Neuron-Specific Enolase Levels Predict the Efficacy of First-Line Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitors in Patients With Non-Small Cell Lung Cancer Harboring EGFR Mutations
Keywords: تومور ناهمگونی; NSE; Predictive value; Prognosis; Progression-free survival; Tumor heterogeneity;
The link between diffusion MRI and tumor heterogeneity: Mapping cell eccentricity and density by diffusional variance decomposition (DIVIDE)
Keywords: تومور ناهمگونی; Tumor heterogeneity; Microscopic anisotropy; Diffusional variance; Diffusional kurtosis; Diffusion tensor distribution; Quantitative microscopy;
DEMARCATE: Density-based magnetic resonance image clustering for assessing tumor heterogeneity in cancer
Keywords: تومور ناهمگونی; Glioblastoma; Medical imaging; Tumor heterogeneity; Density estimation; Clustering; Fisher–Rao metric
ReviewHeralding a new paradigm in 3D tumor modeling
Keywords: تومور ناهمگونی; 3D tumor models; Patient-derived xenografts; Organoids; Cancer; Tumor heterogeneity; Tumor microenvironment;
Analysis of three leakage-correction methods for DSC-based measurement of relative cerebral blood volume with respect to heterogeneity in human gliomas
Keywords: تومور ناهمگونی; rCBV; relative cerebral blood volume; K2; permeability related fitting parameter; CA; contrast agent; SVD; singular value decomposition; DSC; dynamic susceptibility contrast; PB; pre-bolus; MTT; mean transit time; BBB; blood-brain-barrier; WM; white mat
Summary of the 2015 American Association for Cancer Research (AACR) Annual Meeting
Keywords: تومور ناهمگونی; Personalized therapy; Immunotherapy; Resistance to cancer therapies; Tumor heterogeneity; Preclinical models; Tumor microenvironment; Dormancy; Cancer genetics;
Concurrence of EGFR amplification and sensitizing mutations indicate a better survival benefit from EGFR-TKI therapy in lung adenocarcinoma patients
Keywords: تومور ناهمگونی; Lung adenocarcinoma; Epidermal growth factor receptor; Mutation; Gene amplification; Tyrosine kinase inhibitor; Tumor heterogeneity;
Clonality analysis in primary oral squamous cell carcinoma and related lymph-node metastasis revealed by TP53 and mitochondrial DNA next generation sequencing analysis
Keywords: تومور ناهمگونی; Oral squamous cell carcinoma; Lymph-node metastasis; TP53 sequence analysis; Mitochondrial DNA analysis; Tumor heterogeneity
Cluster analysis of quantitative parametric maps from DCE-MRI: application in evaluating heterogeneity of tumor response to antiangiogenic treatment
Keywords: تومور ناهمگونی; DCE-MRI; Gd-complexes; Pharmacokinetic modeling; Clustering; Antiangiogenic; Tumor heterogeneity;
Depletion of poly(A)-specific ribonuclease (PARN) inhibits proliferation of human gastric cancer cells by blocking cell cycle progression
Keywords: تومور ناهمگونی; BSA; bovine serum albumin; CDK; cyclin-dependent kinase; DDR; DNA damage response; DMEM; Dulbecco's modified Eagle's medium; EEP; endonuclease-exonuclease-phosphatase; HRP; Horseradish peroxidase; HU; hydroxyl urea; M-MLV; Moloney murine leukemia viru
Complex adaptive therapeutic strategy (CATS) for cancer
Keywords: تومور ناهمگونی; Tumor heterogeneity; Complex adaptive system (CAS); Induced phenotype; Tumor network; Cancer immunotherapy; Nanoparticle
Review - Part of the Special Issue: Metabolism 2014 - Alterations of metabolic pathways as therapeutic targetsMetabolic orchestration between cancer cells and tumor microenvironment as a co-evolutionary source of chemoresistance in ovarian cancer: A the
Keywords: تومور ناهمگونی; Ovarian cancer; Metabolism; Chemoresistance; Tumor microenvironments; Tumor heterogeneity;
pH-responsive and charge shielded cationic micelle of poly(l-histidine)-block-short branched PEI for acidic cancer treatment
Keywords: تومور ناهمگونی; pH-sensitive block copolymer; Extracellular pH; Paclitaxel; Micelle; Tumor heterogeneity; Poly(l-histidine);
State of the Art Radiation Therapy for Lung Cancer 2012: A Glimpse of the Future
Keywords: تومور ناهمگونی; Decision support; Individualized; Non–small-cell lung cancer; Radiation therapy; Small-cell lung cancer; Tumor heterogeneity
Impact of host ageing on the metastatic phenotype
Keywords: تومور ناهمگونی; LLC, Lewis lung carcinoma; ECIS, electrical cell-substrate impedance sensingAgeing; Tumor dissemination; Tumor heterogeneity; Cellular impedance
Tumor heterogeneity and its implication for drug delivery
Keywords: تومور ناهمگونی; Tumor heterogeneity; Drug delivery; Cancer stem cell; Tumor microenvironment
Characterizing Tumor Heterogeneity With Functional Imaging and Quantifying High-Risk Tumor Volume for Early Prediction of Treatment Outcome: Cervical Cancer as a Model
Keywords: تومور ناهمگونی; Tumor heterogeneity; Magnetic resonance imaging (MRI); Dynamic contrast enhanced (DCE) MRI; Cervical cancer; Anatomic tumor volume; Functional tumor imaging;
Microcirculatory fraction (MCFI) as a potential imaging marker for tumor heterogeneity in breast cancer
Keywords: تومور ناهمگونی; Tumor heterogeneity; Response assessment; Breast cancer; DCE-MRI;
The Epidemiology of Endometrial and Ovarian Cancer
Keywords: تومور ناهمگونی; Ovarian cancer; Endometrial cancer; Tumor heterogeneity; Risk factors;
Odyssey of a cancer nanoparticle: From injection site to site of action
Keywords: تومور ناهمگونی; Drug delivery; Nanomedicine; Cancer; EPR; Extravasation; Diffusion; Tumor heterogeneity; Multidrug resistance
Epigenetic mechanisms in tumorigenesis, tumor cell heterogeneity and drug resistance
Keywords: تومور ناهمگونی; Acquired drug resistance; Tumor heterogeneity; Epigenetics; Oncogenic histone modifications; Epigenetic therapy;
Metastatic Lymph Node Targeted Chemosensitivity Test for Gastric Cancer
Keywords: تومور ناهمگونی; chemosensitivity test; tumor heterogeneity; gastric cancer
Cancer associated fibroblasts in cancer pathogenesis
Keywords: تومور ناهمگونی; Cancer associated fibroblast; Stromal-epithelial interaction; Tumor heterogeneity; Tumor stroma; Activated fibroblasts; Myofibroblasts;
The quantitative detection of total HER2 load by quantum dots and the identification of a new subtype of breast cancer with different 5-year prognosis
Keywords: تومور ناهمگونی; Quantum dots; Breast carcinoma; HER2; Tumor heterogeneity; Quantitative determination; Survival analysis
Overexpression of COX-2 in Celecoxib-Resistant Breast Cancer Cell Lines
Keywords: تومور ناهمگونی; breast cancer; inflammatory breast cancer; tumor heterogeneity; COX-2; metastasis; apoptosis; targeted therapy; therapy resistance
Multifocal prostate cancer: biologic, prognostic, and therapeutic implications
Keywords: تومور ناهمگونی; Prostate; Prostatectomy; Multifocal; Tumor heterogeneity; Carcinogenesis; Precursor lesions; Prostatic intraepithelial neoplasia (PIN); Field effect; Tumor volume; Staging; Gleason grade; Molecular genetics; TMPRSS2-ERG gene fusion
Tracing the tumor lineage
Keywords: تومور ناهمگونی; Tumor progression; Tumor heterogeneity; Copy number aberrations; CGH microarrays; Cancer phylogenetics
In vitro chemosensitivity based on depth of invasion in advanced colorectal cancer using ATP-based chemotherapy response assay (ATP-CRA)
Keywords: تومور ناهمگونی; ATP-based chemotherapy response assay (ATP-CRA); Colorectal cancer; Tumor heterogeneity
Tumor Heterogeneity of FIGO Stage III Carcinoma of the Uterine Cervix
Keywords: تومور ناهمگونی; Radiotherapy; Uterine cervical cancer; FIGO Stage III; Tumor heterogeneity;
Exploring feature-based approaches in PET images for predicting cancer treatment outcomes
Keywords: تومور ناهمگونی; Positron emission tomography; Treatment outcomes; Uptake values; Image morphology; Intensity–volume histograms; Co-occurrence matrix; Tumor shape; Tumor heterogeneity
Tumor heterogeneity in ovarian cancer as demonstrated by in vitro chemoresistance assays
Keywords: تومور ناهمگونی; Tumor heterogeneity; Chemotherapy; Ovarian cancer; In vitro chemoresistance assays
Stability of 18F-Deoxyglucose Uptake Locations Within Tumor During Radiotherapy for NSCLC: A Prospective Study
Keywords: تومور ناهمگونی; FDG uptake; Non-small-cell lung cancer; Positron emission tomography-computed tomography; Adaptive radiotherapy; Tumor heterogeneity;
Radiobiologic Significance of Response of Intratumor Quiescent Cells In Vivo to Accelerated Carbon Ion Beams Compared With γ-Rays and Reactor Neutron Beams
Keywords: تومور ناهمگونی; Quiescent cell; Carbon ion beam; Reactor neutron beam; γ-Ray; Tumor heterogeneity;
Improved T1-weighted dynamic contrast-enhanced MRI to probe microvascularity and heterogeneity of human glioma
Keywords: تومور ناهمگونی; Tumor heterogeneity; Relative cerebral blood volume; Algorithm; T1-weighted imaging; Dynamic contrast enhancement
Challenges of biological realism and validation in simulation-based medical education
Keywords: تومور ناهمگونی; Medical education; Simulation; Cancer education; Agent-based modeling; Random number generators; Cancer; Tumor heterogeneity; Knowledge acquisition
Conservation of in vitro drug resistance patterns in epithelial ovarian carcinoma
Keywords: تومور ناهمگونی; Chemoresistance assay; Acquired resistance; Tumor heterogeneity;