
Disruption of HNF1α binding site causes inherited severe unconjugated hyperbilirubinemia
Keywords: CAR, Constitutive androstane receptor; CNS, Crigler-Najjar syndrome; gtPBREM, phenobarbital-responsive enhancer module; HNF1α, Hepatic nuclear factor 1α; NT, nucleotide; PXR, Pregnane X Receptor; UCB, unconjugated bilirubin; UGT1A1, Uridine Diphosphate Gl