Synthesis and biological evaluation of phosphate isosters of fosmidomycin and analogs as inhibitors of Escherichia coli and Mycobacterium smegmatis 1-deoxyxylulose 5-phosphate reductoisomerases
Keywords: DXP; 1-deoxy-d-xylulose 5-phosphate; DXR; 1-deoxy-d-xylulose 5-phosphate reductoisomerase; MEP; 2-C-methyl-d-erythritol 4-phosphate; GlpT; glycerol-3-phosphate transporter; UhpT; hexose-6-phosphate transporter; FosR; fosmidomycin resistant strain of E. co