Co-mutation of histone H2AX S139A with Y142A rescues Y142A-induced ionising radiation sensitivity
Keywords: H2AX; Y142; S139; DSB; IR; 53BP1DSB, DNA double strand break; IR, ionising radiation; WSTF, Williams–Beuren syndrome transcription factor kinase; IRIF, ionising radiation induced foci; WT, Wild type; F, phenylalanine; W, tryptophan; A, alanine; Y, tyrosin