دانلود مقالات ISI درباره Wee1 + ترجمه فارسی

Increased activity of both CDK1 and CDK2 is necessary for the combinatorial activity of WEE1 inhibition and cytarabine

Keywords: WEE1; AZD1775; Cytarabine; Leukemia; CDK1; CDK2; DNA damage; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2018 سفارش ترجمه

Identification of PKMYT1 inhibitors by screening the GSK published protein kinase inhibitor set I and II

Keywords: Cdk1; Cyclin-dependent kinase 1; EFS; embryonal FYN-associated substrate; (6-FAM); 6-carboxyfluorescein; FL; full-length; FP; fluorescence polarization; FPIA; fluorescence polarization based immunoassay; KD; kinase domain; PKIS; protein kinase inhibitor s

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Radiobiology of head and neck cancerG2-checkpoint targeting and radiosensitization of HPV/p16-positive HNSCC cells through the inhibition of Chk1 and Wee1

Keywords: HPV; HNSCC; Chk1; Wee1; G2-arrest; Radiosensitization;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Original ArticleImproving pharmacological targeting of AKT in melanoma

Keywords: Melanoma; AKT3; WEE1; MK1775; GDC0068; AZD5363 and synergy;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Original ArticleMutations of the LIM protein AJUBA mediate sensitivity of head and neck squamous cell carcinoma to treatment with cell-cycle inhibitors

Keywords: Polo-like kinase 1; Head neck squamous cell carcinoma; WEE1; CHK1; AJUBA; AUC; area under the curve; BrdU; bromodeoxyuridine; CCC; concordance correlation coefficient; CHK1/2; checkpoint kinases 1 and 2; FDR; false-discovery rate; HNSCC; head and neck squ

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

DNA damage response inhibitors: Mechanisms and potential applications in cancer therapy

Keywords: ATM; ATR; CHK1; WEE1; DNA damage response; Targeted therapy; Combination strategies;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Update on rational targeted therapy in AML

Keywords: High-risk AML; IDH; BET; HDAC inhibitors; LSD1; DOT1L; Flavopiridol; Palbociclib; Volasertib; Wee1; Idasanutlin; Aurora kinase; Rigosertib; Hedgehog; BH3-mimetic; Venetoclax; Pevonedistat; Tosedostat

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

PKC-alpha modulation by miR-483-3p in platinum-resistant ovarian carcinoma cells

Keywords: API5; apoptosis inhibitor 5; ARF1; ADP ribosylation factor 3; BCA; bicinchoninic acid; BBC3/PUMA; BCL2 binding component 3; BIRC5; baculoviral IAP (inhibitor of apoptosis) repeat containing 5; CDC25A; cell division cycle 25A; CDK4; cyclin-dependent kinase

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

WEE1 is a validated target of the microRNA miR-17-92 cluster in leukemia

Keywords: MicroRNA; miR-17-92; WEE1; leukemia; kinase;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Radiosensitization of metformin in pancreatic cancer cells via abrogating the G2 checkpoint and inhibiting DNA damage repair

Keywords: Metformin; Radiosensitizer; Pancreatic cancer; Wee1; Rad51; mTOR;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Proteomic analysis of cell proliferation in a human hepatic cell line (HL-7702) induced by perfluorooctane sulfonate using iTRAQ

Keywords: MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; iTRAQ; isobaric tags for relative and absolute quantitation; Cdks; cyclin-dependent kinases; Myc; myelocytomatosis oncogene; Myt1; myelin transcription factor 1; Wee1; G2 checkpoint kinase

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Chk1 and Wee1 control genotoxic-stress induced G2-M arrest in melanoma cells

Keywords: Tumour biology; Cell signalling; Cell cycle; Chk1; Wee1;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Wee1 is a novel independent prognostic marker of poor survival in post-chemotherapy ovarian carcinoma effusions

Keywords: Wee1; Ovarian carcinoma; Effusions; Tumor progression; Survival;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

CHEK again: Revisiting the development of CHK1 inhibitors for cancer therapy

Keywords: CHK1; Checkpoint kinase 1; DNA replication; WEE1; DNA damage responseATM, ataxia-telangiectasia mutated; ATR, ATM and Rad3 related; CHK1, Checkpoint Kinase 1; CHK2, Checkpoint Kinase 2; CDKs, Cyclin-dependent kinases; DDK, DBF4/DRF1-dependent CDC7 kinase;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Lessons from the gene expression pattern of the rat zona glomerulosa

Keywords: zG; zona glomerulosa; zF; zona fasciculata; zR; zona reticularis; Cyp11b1; steroid 11β-hydroxylase; Cyp11b2; aldosterone synthase; TGF-β; transforming growth factor β; Gpc3; glypican 3; Kcnn2; potassium intermediate/small conductance calcium-activated

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

WEE1 tyrosine kinase, a novel epigenetic modifier

Keywords: WEE1; histones; tyrosine phosphorylation; epigenetics; cancer; cell cycle

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

The miR-290-295 cluster promotes pluripotency maintenance by regulating cell cycle phase distribution in mouse embryonic stem cells

Keywords: Embryonic stem cells; MicroRNAs; miR-290-295 cluster; Differentiation; Fbxl5; Wee1

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2011 سفارش ترجمه

Cell cycle arrest as a hallmark of insect diapause: Changes in gene transcription during diapause induction in the drosophilid fly, Chymomyza costata

Keywords: Drosophila; Cell cycle arrest; Diapause; Cyclins; Dacapo; PCNA; Wee1; Myt1; String

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Synthesis and structure–activity relationships of N-6 substituted analogues of 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of Wee1 and Chk1 checkpoint kinases

Keywords: Phenylpyrrolocarbazole; Wee1; Chk1; G2/M checkpoint abrogation

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2008 سفارش ترجمه

Silence is Golden: Combining RNAi and live cell imaging to study cell cycle regulatory genes during Caenorhabditis elegans development

Keywords: C. elegans; RNAi; Oocyte maturation; Wee1

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

HIV-1 Vpr induces G2 cell cycle arrest in fission yeast associated with Rad24/14-3-3-dependent, Chk1/Cds1-independent Wee1 upregulation

Keywords: HIV-1; Vpr; Cell cycle; Fission yeast; Wee1; Chk1; Cds1; Rad24; 14-3-3

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Identification of a novel Wee1 isoform

Keywords: Wee1; Wee1 isoform; Cyclin-dependent kinase; Cell cycle regulation; Neuron; Differentiation;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Circadian clocks: Neural and peripheral pacemakers that impact upon the cell division cycle

Keywords: Cell cycle; Cell division; Circadian; Clock; Cryptochrome; Cyclin D1; E-box; Luciferase; Per2; Period; Suprachiasmatic; Wee1;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2005 سفارش ترجمه