Keywords: MFGM; milk fat globule membrane; NMJ; neuromuscular junction; EDL; extensor digitorum longus; AChR; acetylcholine receptors; α-BTX; α-bungarotoxin; LRP4; LDL Receptor Related Protein 4; Aging; Exercise; Milk fat globule membrane; Motor function; Neuromu
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Keywords: ACh; acetylcholine; α-BTX; α-bungarotoxin; Carb; carbamylcholine; Chol; cholesterol; ECD; extracellular domain; ELIC; Erwinia ligand-gated ion channel; GLIC; Gloebacter ligand-gated ion channel; nAChR; nicotinic acetylcholine receptor; PA; 1-palmitoyl-2
Keywords: MG; myasthenia gravis; AChR; nicotinic acetylcholine receptor; ECD; extracellular domain; MIR; main immunogenic region; AChBP; acetylcholine binding protein; α-Btx; α-bungarotoxin.; Nicotinic acetylcholine receptor; Extracellular domain; Myasthenia grav
Keywords: α7ânAChR; alpha7 subunit-containing nicotinic receptor; α-btx; alpha bungarotoxin; BSA; bovine serum albumin; D-AP5; D-(â)-2-amino-5-phosphonopentanoic acid; DG; dentate gyrus; DhβE; dihydro-Ã-erythrodine; GAD67; glutamate decarboxylase 67; GFP; g
Keywords: α-BTX; α-bungarotoxin; AChR; acetylcholine receptor; BSA; bovine serum albumin; DABCO; 1,4-diazabicyclo[2.2.2]octane; FDB; flexor digitorum brevis; FDL; flexor digitorum longus; NMJ; neuromuscular junction; PFA; paraformaldehyde; Lower motor neuron; Lum
Keywords: Cyclic imines; Nicotinic acetylcholine receptors; α-bungarotoxin; Competition assay; Single-laboratory pre-validation; BSA; Bovine serum albumin; α-BTX; α-bungarotoxin; CR; cross-reactivity; CV; coefficient of variation; HRP; horseradish peroxidase; i.
Heterogeneity of auto-antibodies against nAChR in myasthenic serum and their pathogenic roles in experimental autoimmune myasthenia gravis
Keywords: Ab; antibody; α-Btx; alpha-Bungarotoxin; CDC; complement dependent cytotoxicity; cpm; count per minute; Cmax; maximum plasma concentration; EAMG; experimental autoimmune myasthenia gravis; EDL; extensor digitorum longus; Fab; Fab fragment of monoclonal a
Tricyclic antidepressants inhibit hippocampal α7* and α9α10 nicotinic acetylcholine receptors by different mechanisms
Keywords: AChR; nicotinic acetylcholine receptor; ACh; acetylcholine; TCAs; tricyclic antidepressants; α-BTx; α-bungarotoxin; MLA; methyllycaconitine; RT; room temperature; IC50; ligand concentration that produces 50% inhibition (of binding or of agonist activati
Characterization of a reproducible rat EAMG model induced with various human acetylcholine receptor domains
Keywords: MG; myasthenia gravis; AChR; nicotinic acetylcholine receptor; ECD; extracellular domain; MIR; main immunogenic region; AChBP; acetylcholine binding protein; α-Btx; α-bungarotoxin; EAMG; experimental autoimmune myasthenia gravis; EMG; electromyography;
Increased BACE1 activity inhibits peripheral nerve regeneration after injury
Keywords: WT; Wild type; Tg; Transgenic; BACE1; Beta-amyloid cleaving enzyme 1; APP; amyloid precursor protein; PNS; peripheral nervous system; CMAP; compound muscle action potential; MBP; myelin basic protein; AD; Alzheimer's disease; NF; neurofilament; α-BTX; α
Functional characterization of two prokaryotic pentameric ligand-gated ion channel chimeras - role of the GLIC transmembrane domain in proton sensing
Keywords: 5HT3R; serotonin receptor; α-BTX; α-bungarotoxin; AChBP; acetylcholine-binding protein; ECD; extracellular domain; ELIC; Erwinia ligand-gated ion channel; GLIC; Gloebacter ligand-gated ion channel; GlyR; glycine receptor; nAChR; nicotinic acetylcholine
Neuromuscular paralysis by the basic phospholipase A2 subunit of crotoxin from Crotalus durissus terrificus snake venom needs its acid chaperone to concurrently inhibit acetylcholine release and produce muscle blockage
Keywords: Crotalus durissus terrificus; Crotalinea Snake Venom; Phospholipase A2; [3H]-Acetylcholine Release; Real-time transmitter exocytosis; Neuromuscular transmission; [3H]-ACh; [3H]-acetylcholine; α-BTX; α-bungarotoxin; CA; acidic subunit; CB; basic PLA2 sub
Assessment of the functionality and stability of detergent purified nAChR from Torpedo using lipidic matrixes and macroscopic electrophysiology
Keywords: nAChR-DCs; nicotinic acetylcholine receptors detergent complexes; Tc; Torpedo californica; Tm; Torpedo marmorata; PLB; planar lipid bilayer; TEVC; two electrode voltage clamp; LCP; Lipidic Cubic Phase; FC; foscholine family 12-16 carbon chain; LFC; lyso
Lithium accelerates functional motor recovery by improving remyelination of regenerating axons following ventral root avulsion and reimplantation
Keywords: α-BTX; α-bungarotoxin; AchRs; acetylcholine receptors; BDNF; brain-derived neurotrophic factor; BPI; brachial plexus injury; CMAP; compound muscle action potential; CNS; central nervous system; CNTF; ciliary neurotrophic factor; CSPG; chondroitin sulfat
Macrophage-mediated inflammation and glial response in the skeletal muscle of a rat model of familial amyotrophic lateral sclerosis (ALS)
Keywords: α-BTX; alpha-bungarotoxin; AChR; acetylcholine receptor; ALS; amyotrophic lateral sclerosis; ANOVA; analysis of variance; BBB; Basso-Beattie-Bresnahan hindlimb locomotor rating; BVC; bupivacaine hydrochloride; CD11b; cluster of differentiation 11b; C
Ocular myasthenia gravis induced by human acetylcholine receptor ϵ subunit immunization in HLA DR3 transgenic mice
Keywords: MG; myasthenia gravis; AChR; acetylcholine receptor; NMJ; neuromuscular junction; EOM; extraocular muscle; oMG; ocular MG; gMG; generalized MG; EAMG; experimental autoimmune myasthenia gravis; HLA; human leukocyte antigen; E. coli; Escherichia coli; H-ACh
The coupling interface and pore domain codetermine the single-channel activity of the α7 nicotinic receptor
Keywords: Nicotinic receptor; Patch-clamp; Channel gating; Channel coupling; nAChR; nicotinic acetylcholine receptor; ACh; acetylcholine; α-BTX; alpha-bungarotoxin; LGIC; ligand-gated ion channel; 5-HT3R; serotonin receptor type 3; GABAR; γ-aminobutyric acid rece
Pharmacological and molecular studies on the interaction of varenicline with different nicotinic acetylcholine receptor subtypes. Potential mechanism underlying partial agonism at human α4β2 and α3β4 subtypes
Keywords: nAChR; nicotinic acetylcholine receptor; [3H]MLA; [3H]methyllycaconitine; [3H]TCP; piperidyl-3, 4-3H(N)]-(N-(1-(2 thienyl)cyclohexyl)-3, 4-piperidine; α-BTx; α-bungarotoxin; Varenicline; 7,8,9,10-tetrahydro-6,10-methano-6H-azepino[4,5-g]quinoxaline; RT;
Effects of 5α-cholestan-3-one on the synaptic vesicle cycle at the mouse neuromuscular junction
Keywords: α-Btx; α-bungarotoxin; 5Ch3; 5α-cholestan-3-one; CYP27A; cytochrome P450 enzyme, sterol 27-hydroxylase; EPC; postsynaptic end-plate currents; 22NBD-cholesterol; 22-(N-(7-Nitrobenz-2-Oxa-1,3-Diazol-4-yl)Amino)-23,24-Bisnor-5-Cholen-3β-Ol; MCD; methyl-Î
Basic NeuroscienceMicrofluidic primary culture model of the lower motor neuron-neuromuscular junction circuit
Keywords: α-BTx; α-bungarotoxin; AChR; acetylcholine receptor; DIV; days in vitro; HBSS; Hanks balanced salt solution; NMJ; neuromuscular junction; PDMS; poly(dimethylsiloxane); Microfluidic; Motor neuron; Muscle; Neuromuscular junction; Cell culture;
(â)-Reboxetine inhibits muscle nicotinic acetylcholine receptors by interacting with luminal and non-luminal sites
Keywords: AChR; nicotinic acetylcholine receptor; NSRI; norepinephrine selective reuptake inhibitor; TCAs; tricyclic antidepressants; NCA; non-competitive antagonist; (â)-reboxetine; (â)-R,R-([2-[α[2-ethoxyphenoxy]benzyl]-morpholine); PCP; phencyclidine; [3H]T
Differential targeting of immune-cells by Pixantrone in experimental myasthenia gravis
Keywords: AChR; acetylcholine receptor; TAChR; Torpedo acetylcholine receptor; BZ; Bortezomib; α-BTX; α-bungarotoxin; Ct; cycle threshold; EAMG; experimental autoimmune myasthenia gravis; LNCs; lymph node cells; MTX; mitoxantrone; MG; myasthenia gravis; MMF; myco
Structural and functional interaction of (±)-2-(N-tert-butylamino)-3â²-iodo-4â²-azidopropiophenone, a photoreactive bupropion derivative, with nicotinic acetylcholine receptors
Keywords: AChR; nicotinic acetylcholine receptor; NCA; noncompetitive antagonist; α-BTx; α-bungarotoxin; BP; (±)-bupropion [(±)-2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one]; (±)-SADU-3-72; (±)-2-(N-tert-butylamino)-3â²-iodo-4â²-azidopropiophenone; PC
Distinct localization of collagen Q and PRiMA forms of acetylcholinesterase at the neuromuscular junction
Keywords: α-BTX; α-bungarotoxin; ACh; acetylcholine; AChE; acetylcholinesterase; AChE1irr; mouse strain lacking AChE expression in muscle; BChE; butyrylcholinesterase; ChT; high affinity choline transporter; ColQ; collagen Q; nAChR; nicotinic acetylcholine recept
Research ReportOlfactory discrimination varies in mice with different levels of α7-nicotinic acetylcholine receptor expression
Keywords: α7; α7-nicotinic acetylcholine receptor; nAChR; nicotinic acetylcholine receptor; +/+; wild type; +/â; heterozygous knock-out; â/â; homozygous knock-out; α-BTX; [125I] α-bungarotoxin; OB; olfactory bulb; HDB; horizontal limb of the diagonal band
Chrna7 genotype is linked with alpha7 nicotinic receptor expression but not alpha7 RNA levels
Keywords: UTR; Untranslated region; α-BTX; α-bungarotoxin; nAChR; Nicotinic acetylcholine receptor; Nicotinic receptor; Genetics; Mice; Gene expression; Post-transcriptional;
Developmental regulation of nicotinic acetylcholine receptors within midbrain dopamine neurons
Keywords: adolescent; fetal; nicotine; sex; striatum; maternal smoking; α-BTX; α-bungarotoxin; DA; dihydroxyphenylethylamine dopamine; Dig; digoxygenin; G; gestational day; GB; Genius buffer; nAChR; nicotinic acetylcholine receptor; NIC; nicotine; P; postnatal da
Apisα2, Apisα7-1 and Apisα7-2: three new neuronal nicotinic acetylcholine receptor α-subunits in the honeybee brain
Keywords: nAChRs; nicotinic acetylcholine receptors; CNS; central nervous system; ACh; acetylcholine; AChE; acetylcholine esterase; α-Btx; alpha-bungarotoxin; TM; transmembrane domain; dl; dorsal lobe; la; lamina; me; medulla; ca; calice; al; antennal lobe; ich; i
Internalization of a GFP-tetanus toxin C-terminal fragment fusion protein at mature mouse neuromuscular junctions
Keywords: α-BTX; α-bungarotoxin; β-gal; β-galactosidase; β-gal-TTC; fusion protein of β-gal and C-terminal fragment of tetanus toxin; CT-B; AlexaFluor 594-conjugated B-subunit of cholera toxin; GFP; green fluorescent protein; GFP-TTC; fusion protein of GFP an
LNX1 is a perisynaptic Schwann cell specific E3 ubiquitin ligase that interacts with ErbB2
Keywords: NMJ; Neuromuscular junction; PSC; Perisynaptic Schwann cell; PBS; Phosphate buffered saline; PDZ; PSD-95, DlgA, ZO-1; α-Btx;  α-bungarotoxin; TTX; tetrodotoxin;
Tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces cell proliferation in normal human bronchial epithelial cells through NFκB activation and cyclin D1 up-regulation
Keywords: NNK; 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone; NHBE; normal human bronchial epithelial cell; SAEC; small airway epithelial cell; nAchR; nicotinic acetylcholine receptor; DHβE; dihydro-β-erythroidine; α-BTX; α-bungarotoxin; MLA; methyllycaconitin