دانلود مقالات ISI درباره Β-Secretase (Bace1) + ترجمه فارسی

Design and synthesis of novel coumarin-pyridinium hybrids: In vitro cholinesterase inhibitory activity

Keywords: Cholinesterases; Coumarins; Docking study; Kinetic study; Pyridinium salts; β-secretase (BACE1);

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Identification of new BACE1 inhibitors using Pharmacophore and Molecular dynamics simulations approach

Keywords: Alzheimer disease; β-Secretase (BACE1); Pharmacophore-based virtual screening (PBVS); Molecular dynamics; Binding free energy calculation;

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2017 سفارش ترجمه

Discovery of polymethoxyflavones from black ginger (Kaempferia parviflora) as potential β-secretase (BACE1) inhibitors

Keywords: Aβ; β-amyloid peptide; AD; Alzheimer's disease; APP; Amyloid precursor protein; BACE1; β-site amyloid precursor protein cleaving enzyme 1; BBB; Blood-brain barrier; DMF; 5,7-dimethoxyflavone; KP; Kaempferia parviflora; PMF; 3,5,7,3′,4′-pentametho

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

4-O-galloylalbiflorin discovered from Paeonia lactiflora Pall. is a potential β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor

Keywords: Alzheimer's disease (AD); β-secretase (BACE1); β-amyloid peptide; Paeonia lactiflora Pall; 4-O-galloylalbiflorin; Docking; Aβ; β-amyloid peptide; AD; Alzheimer's disease; APP; amyloid precursor protein; BACE1; β-site amyloid precursor protein cleavin

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Development of 2-aminooxazoline 3-azaxanthenes as orally efficacious β-secretase inhibitors for the potential treatment of Alzheimer's disease

Keywords: Alzheimer's disease (AD); β-Secretase (BACE1); Aminooxazoline; Xanthene; 3-Azaxanthene; Amyloid; Aβ peptides;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Biological evaluation and in silico docking study of γ-linolenic acid as a potential BACE1 inhibitor

Keywords: Alzheimer's disease; β-secretase (BACE1); β-amyloid peptide (Aβ); γ-linolenic acid;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Conformational restriction approach to BACE1 inhibitors II: SAR study of the isocytosine derivatives fixed with a cis-cyclopropane ring

Keywords: Alzheimer's disease; β-Secretase (BACE1); Conformational restriction; Cyclopropane;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse models

Keywords: Nicotinamide riboside; Alzheimer's disease; β-secretase (BACE1); Promotes peroxisome proliferator-activated receptor (PPAR)-γ coactivator 1 (PGC)-1α; Ubiquitin-proteasome system; Mitochondrial metabolism; Synaptic plasticity; Long-term potentiation;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Conformational restriction approach to β-secretase (BACE1) inhibitors III: Effective investigation of the binding mode by combinational use of X-ray analysis, isothermal titration calorimetry and theoretical calculations

Keywords: Alzheimer's disease; β-Secretase (BACE1); Conformational restriction; Cyclopropane; Isothermal titration calorimetry;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2013 سفارش ترجمه