کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10051512 | 1599033 | 2005 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
AEROSOL TRANSFER OF BLADDER UROTHELIAL AND SMOOTH MUSCLE CELLS ONTO DEMUCOSALIZED COLONIC SEGMENTS FOR PORCINE BLADDER AUGMENTATION IN VIVO: A 6-WEEK EXPERIMENTAL STUDY
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موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
بیماریهای کلیوی
پیش نمایش صفحه اول مقاله

چکیده انگلیسی
The addition of aerosolized cells of urological origin is a viable augmentation approach that appears to achieve the much sought after inhibition of intrinsic fibrosis and contraction of colonic segments when incorporated into the urinary tract without this cellular component. Moreover, this technique appears to provide a histologically normal, confluent urothelium, which sets the stage for prevention of the well-documented biochemical aberrations inherent in augments containing gastrointestinal epithelium. While successful in this model regardless of the incorporation of urological smooth muscle cells, chronic studies are now warranted to validate the short-term results as well as determine whether the urological mesenchymal population (smooth muscle) will be required to sustain the uroepithelial phenotype in the long term.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Journal of Urology - Volume 174, Issue 4, Part 2, October 2005, Pages 1663-1668
Journal: The Journal of Urology - Volume 174, Issue 4, Part 2, October 2005, Pages 1663-1668
نویسندگان
ASHRAF T. HAFEZ, KOUROSH AFSHAR, DARIUS J. BÃGLI, ANDRE BAHORIC, KAREN AITKEN, CHARLES R. SMITH, ANTOINE E. KHOURY,