کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10066733 | 1600451 | 2005 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Inflammatory bowel disease and preterm delivery
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
زنان، زایمان و بهداشت زنان
پیش نمایش صفحه اول مقاله

چکیده انگلیسی
Objective: The present study investigates pregnancy outcome in women with IBD and examines the effect of pregnancy on the severity of IBD. Method: A case-control study comparing deliveries by mothers with IBD between January 1988 and January 2005 was performed. For every birth by a mother with IBD, four births by non-IBD mothers were randomly selected and adjusted for ethnicity and year of delivery. Result: During the study period there were 48 deliveries to patients with Crohn's disease and 79 deliveries to patients with ulcerative colitis. Higher rates of preterm delivery (<Â 37 weeks) were found among patients with IBD as compared to the controls (odds ratios (OR)Â =Â 2.2; 95% confidence interval (CI)Â =Â 1.3-3.8). This association remained significant after adjustment for labor induction and multiple gestations, using the Mantel-Haenszel technique (weighted ORÂ =Â 2.1; 95% CI 1.3-3.5 and weighted ORÂ =Â 2.0; 95% CI 1.2-3.5; PÂ =Â 0.012; respectively). In addition, these patients had higher rates of fertility treatments (ORÂ =Â 2.2; 95% CIÂ =Â 1.1-4.4). Using a multivariate analysis, controlling for maternal age and fertility treatments, preterm delivery was seen to be significantly associated with IBD (adjusted ORÂ =Â 2.0; 95% CIÂ =Â 1.2-3.5). Perinatal outcomes, such as perinatal mortality, low Apgar scores, and congenital malformations, were comparable to the outcomes in the control group. Conclusion: Maternal IBD is an independent risk factor for preterm delivery. IBD is not associated with adverse perinatal outcome.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Gynecology & Obstetrics - Volume 90, Issue 3, September 2005, Pages 193-197
Journal: International Journal of Gynecology & Obstetrics - Volume 90, Issue 3, September 2005, Pages 193-197
نویسندگان
Gabby Elbaz, Alex Fich, Amalia Levy, Gershon Holcberg, Eyal Sheiner,