Subcutaneous Epithelioid Sarcoma Originating from Multiple Metastases of Uterine Leiomyosarcoma

The abrupt appearance of skin or subcutaneous nodules should prompt the clinician to consider the possibility of metastatic disease, even in patients with no known history of malignant neoplasms. Uterine leiomyosarcomas are rarely diagnosed preoperatively, and the prognosis of uterine sarcoma is notorious for its difficult determination. The frequent development of distant metastases is the main reason for the poor survival observed in uterine sarcoma compared with other uterine malignancies.