Incidence of Cytomegalovirus (CMV) Retinitis in Second Eyes of Patients With the Acquired Immune Deficiency Syndrome and Unilateral CMV Retinitis

The risk of second-eye retiniti is substantial in patients with unilateral CMV retinitis but appears to be reduced by anti-CMV therapy and by HAART-induced immune recovery. Patients are at highest risk when CD4+ T cell counts are very low and in the months immediately after CMV retinitis diagnosis.