Effect of recombinant human BMP-2 on the repair of cricoid cartilage defects in young and adult rabbits: A comparative study

rhBMP-2 triggers appositional cartilage growth from the cricoid perichondrium of young rabbits more easily than from that of adult rabbits. The new bone induced by rhBMP-2 showed a similar immunohistochemical and morphological pattern in both age groups of rabbits.