The Spectrum of APC Mutations in Children with Hepatoblastoma from Familial Adenomatous Polyposis Kindreds

Hepatoblastoma is associated with familial adenomatous polyposis (FAP). In a series of 93 patients with hepatoblastoma,8 (8.6%) reported family histories suggestive of FAP. These and a review of reported FAP kindreds with hepatoblastoma may provide information helpful in counseling families with FAP.