کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10155505 | 1666351 | 2018 | 23 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Femtosecond laser impact on calcium phosphate bioceramics assessed by micro-Raman spectroscopy and osteoblastic behaviour
ترجمه فارسی عنوان
اثر لیزر فموتوسجد بر روی فسفات کلسیم بیوسکرمی بررسی شده توسط طیف سنجی میکرو رامان و رفتار استئوبلاستیکی
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موضوعات مرتبط
مهندسی و علوم پایه
مهندسی مواد
سرامیک و کامپوزیت
چکیده انگلیسی
The present work is an investigation of the biological response to the presence of grooves 3â¯Î¼m deep, 15â¯Î¼m wide and spaced by 100â¯Î¼m, produced with femtosecond laser on β-tricalcium phosphate (β-TCP). The heat affected zone generated by the laser irradiation was investigated. Micro-Raman spectroscopy showed a transformation from β-TCP phase into α-TCP phase, localised inside the grooves. The X Ray Diffraction analyses, correlated with micro-Raman data, confirmed that the use of femtosecond pulsed laser enables to limit the thermal impact. A selection of optimised process parameters allowed to obtain β-TCP micro-patterned surfaces avoiding any phase transformation. The increase of the wettability with the micro-patterning, compared to smooth surfaces, was highlighted. An improvement of the osteoblastic proliferation was also demonstrated. Finally, the tendency of cell elongation along the grooves direction showed the ability of osteoblastic cells to adapt their morphology to the support topography on which they grow.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the European Ceramic Society - Volume 38, Issue 16, December 2018, Pages 5545-5553
Journal: Journal of the European Ceramic Society - Volume 38, Issue 16, December 2018, Pages 5545-5553
نویسندگان
Marie Lasgorceix, Liliana Grenho, Maria Helena Fernandes, Cédric Ott, Laurent Boilet, Anne Leriche, Fernando Monteiro, Francis Cambier, Stéphane Hocquet,