Atypical chronological changes on neuroimaging in the epidermoid in the frontal lobe with intracystic hemorrhage and tumor growth: Case report

Intracranial epidermoids are rare lesions accounting for 0.2%-1.8% of all intracranial tumors. They commonly develop in the cerebellopontine angle and the parasellar region and can appear with atypical neuroimaging features due to intracystic hemorrhages which complicate diagnosis. The authors present a case of a 62-year-old woman with a frontal epidermoid cyst with a hemorrhage and tumor growth. A series of atypical radiological findings showed gradual changes in the lesion appearance that were confirmed with surgery and histopathology. To avoid surgical complications such as chemical meningitis, it is important to remember that epidermoid cysts occasionally bleed, leading to atypical MRI and/or CT findings and diagnostic difficulties. Development of epidermoid cysts in atypical locations in the brain may result in challenges to accurate diagnosis.