Attainable region of reactive distillation-Part IV: Inclusion of multistage units for complex reaction schemes

► van de Vusse schemes with both non-azeotropic and azeotropic VLE are considered and the AR is constructed. ► Explanation is provided based on the visualization of selectivity lines in the composition space. ► Presence of binary and multi-component azeotropes can be handled very well by the developed algorithm.