کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10262756 | 457066 | 2005 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Systematic procedure for the reduction of complex biological reaction pathways and the generation of macroscopic equivalents
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
مهندسی شیمی (عمومی)
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چکیده انگلیسی
In this study, a class of dynamic models based on metabolic reaction pathways is analyzed, showing that systems with complex intracellular reaction networks can be represented by macroscopic reactions relating extracellular components only. Based on rigorous assumptions, the model reduction procedure is systematic and allows equivalent `input-output' representations of the system to be derived. The procedure is illustrated with a few examples, and a comparison is made with another recently published method for generating and evaluating macroscopic reaction schemes.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chemical Engineering Science - Volume 60, Issue 2, January 2005, Pages 459-465
Journal: Chemical Engineering Science - Volume 60, Issue 2, January 2005, Pages 459-465
نویسندگان
Jens E. Haag, Alain Vande Wouwer, Philippe Bogaerts,