کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10322755 | 660870 | 2011 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
A new logic correlation rule for HIV-1 protease mutation
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی کامپیوتر
هوش مصنوعی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: A new logic correlation rule for HIV-1 protease mutation A new logic correlation rule for HIV-1 protease mutation](/preview/png/10322755.png)
چکیده انگلیسی
⺠In this paper, a pre and post-processing approach through discovering a logic correlation rule to the mutations of the HIV-1 protease sequences form HIV Drug Resistance Database by combining Apriori-base method and Bool-ean function simplification technique called Apriori_BFS method is presented. ⺠Statistically, the correlation can show whether and how strongly pairs of variables are related. In this study, the logic correlation rule indicates the logic relation between two or more variables; it does not indicate that one variable ''caused'' the other, just which as one variable changes, the other changes likewise. ⺠To design effective HIV protease inhibitors, identifying cleaved HIV subtype is very crucial. Therefore, this study attempted to distinguish the diversity relationship of mutations between subtypes of HIV-1 by discovering the logic correlation rules.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Expert Systems with Applications - Volume 38, Issue 5, May 2011, Pages 5448-5455
Journal: Expert Systems with Applications - Volume 38, Issue 5, May 2011, Pages 5448-5455
نویسندگان
Yi-Chun Lin, Yueh-Min Huang, James Jiunn-Yin Leu,