STEPS: Similarity and Truth Estimation for Propagated Segmentations and its application to hippocampal segmentation and brain parcelation

► New locally ranked label fusion algorithm for multi-atlas segmentation. ► Unbiased performance parameter estimation by consensus voxel removal. ► Overall model parameter optimisation for several types of label fusion techniques. ► Highly accurate unsupervised hippocampal segmentation and full brain parcelation. ► Highly significant group differences in hippocampal atrophy rates between controls, MCI and AD patients.