Using genetic algorithm in reconstructing single individual haplotype with minimum error correction

► We address the shortage of existing methods and solve it via genetic algorithm. ► We design a better fitness function based on the major rule. ► Our method can reconstruct single individual haplotypes with highly reconstruction rate. ► Our method can reconstruct single individual haplotypes with lower minimum error correction (MEC) time. ► We handle the raw input haplotype fragment matrix directly.