Phase behavior and rheological properties of DNA-cationic polysaccharide mixtures

► We have prepared double- or single-stranded DNA/polycation formulations. ► DNA/polycation mixtures presented widely different properties. ► Phase separation was observed at sub-stoichiometric and intermediate charge ratios. ► Redissolved viscoelastic one-phase mixtures formed at a modest excess of polycation. ► We have observed non-monotonic variations in rheological parameters.