Straightforward preparation of organic colloidal particles by harnessing spontaneous non-covalent interactions of active molecules from natural origin

► Non-covalent spontaneous interactions between berberine and tannic acid. ► Stabilisation by Glycyrrhizin due to its interaction with both berberine and tannic acid. ► Straightforward preparation of spherical colloidal particles simply by mixing these components at certain molar ratio. ► Characterisation of particle size, surface potential and morphology.