Biofunctionalization of titanium with PEG and anti-CD34 for hemocompatibility and stimulated endothelialization

► Hemocompatibility of the modified surface is superior to that of titanium. ► The modified surface selectively stimulates EPC adhesion. ► Unfortunately, such surface inhibits EPC proliferation. ► Denatured fibrinogen is the critical determinant of the hemocompatibility. ► Relative stability of the coating makes this technique applicable.