Interfacial properties of hydrophilized poly(lactic-co-glycolic acid) layers with various thicknesses

► Improved surface biocompatibility of PLGA film by blending with Pluronic127. ► Reduced protein adsorption in accordance with surface hydrophilicity and composition. ► Layer thickness greatly affected surface properties and protein repellency of the film. ► Blend layers go through swelling and partial dissolution of Pluronic.