Biophysical investigation of the interfacial properties of cationic fluorocarbon/hydrocarbon hybrid surfactant: Mimicking the lung surfactant protein C

► A new lipid molecule was designed to mimic the selected properties of the lung surfactant. ► The molecule bears a cationic head group and a fluorocarbon chain in its structure. ► It interacts with lipids to adjust the interfacial fluidity, elasticity and the hysteresis. ► Mimicing the lung surfactant behaviour associated with specific lung surfactant protein C is achieved.