کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10393300 | 887766 | 2005 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Calorimetric investigation of the effect of hydroxyanthraquinones in Rheum officinale Baill on Staphylococcus aureus growth
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
جریان سیال و فرایندهای انتقال
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Calorimetric investigation of the effect of hydroxyanthraquinones in Rheum officinale Baill on Staphylococcus aureus growth Calorimetric investigation of the effect of hydroxyanthraquinones in Rheum officinale Baill on Staphylococcus aureus growth](/preview/png/10393300.png)
چکیده انگلیسی
The inhibitory effects of five hydroxyanthraquinones (HAQs) from root and rhizoma of Rheum officinale Baill, a traditional Chinese medicinal (TCM) herb, on Staphylococcus aureus growth were investigated by calorimetry. The power-time curves of S.aureus with and without HAQ were acquired and the extent and duration of inhibitory effects on the metabolism evaluated by growth rate constants (k1, k2), half inhibitory ratio (IC50), maximum heat output (Pmax) and peak time (tp). The value of k1 and k2 of S. aureus in the presence of the five HAQs decreased with the increasing concentrations of HAQs. Moreover, Pmax was reduced and the value of tp increased with increasing concentrations of the five drugs. The inhibitory activity varied for different drugs. IC50 of the five HAQs was 4 μg mlâ1 for emodin, 3.5 μg mlâ1 for rhein, 10 μg mlâ1 for aloe-emodin, 1000 μg mlâ1 for chrysophanol, 1600 μg mlâ1 for physcion. The sequence of antimicrobial activity of the five HAQs: rhein > emodin > aloe-emodin > chrysophanol > physicion.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Thermochimica Acta - Volume 429, Issue 2, 15 May 2005, Pages 167-170
Journal: Thermochimica Acta - Volume 429, Issue 2, 15 May 2005, Pages 167-170
نویسندگان
Wu Yanwen, Gao Wenyuan, Xiao Xiaohe, Liu Yi,