Development of a sensitive SPR biosensor for C-reactive protein (CRP) using plasma-treated parylene-N film

- Optimum plasma treatment conditions (power and time) for parylene-N film were investigated.
- Influence of plasma treatment was analyzed by XPS depth profile and SPR biosensor.
- Enhanced protein immobilization was demonstrated to the parylene-N film with SPR biosensor.
- A sensitive SPR biosensor for C-reactive protein was developed with the parylene-N film.