کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10431037 | 910195 | 2016 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The impact of valve simplifications on left ventricular hemodynamics in a three dimensional simulation based on in vivo MRI data
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
سایر رشته های مهندسی
مهندسی پزشکی
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چکیده انگلیسی
Left ventricle (LV) fluid dynamics and the function of its valves have a crucial impact on clinical diagnosis, treatment and prosthesis design. In this paper, we simulated left ventricular flow using 3D computational fluid dynamics (CFD) based on geometrical and deformational information obtained from MRI. Time variant smoothed LV shapes were extracted from MR images. Corresponding deformation data was interpolated using a cubic-spline interpolation. To evaluate valve influence on LV flow, we compared two planar valve models: physiologically corrected gradually opening/closing model and a simple on/off model. Endocardial displacement was applied to fluid boundary using fluid-structure interaction (FSI) approach. Arbitrary Lagrangian-Eulerian (ALE) formulation was used for unsteady incompressible viscous Newtonian blood flow in the fluid domain. Comparison of results for LV flow with two valve models demonstrated a clear distinction between pressure distribution, velocity distribution, vortex formation/growth/vanishing and energy dissipation especially in the filling phase. Consequently, LV flow simulation by ignoring geometrical details of valves׳ model may lead to non-realistic results in some aspects.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Biomechanics - Volume 49, Issue 9, 14 June 2016, Pages 1482-1489
Journal: Journal of Biomechanics - Volume 49, Issue 9, 14 June 2016, Pages 1482-1489
نویسندگان
Ali Imanparast, Nasser Fatouraee, Farhad Sharif,