کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10431267 | 910211 | 2015 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The effect of resolution on viscous dissipation measured with 4D flow MRI in patients with Fontan circulation: Evaluation using computational fluid dynamics
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کلمات کلیدی
VNRRPALPASVCTcpCIVCMEB - MONE4D Flow MRI - MRI جریان 4DPhase contrast MRI - MRI کنتراست فازsuperior vena cava - بزرگ سیاهرگ بالایی، بزرگ سیاهرگ زبرینVENC - بیاCongenital heart disease - بیماری قلبی مادرزادیViscous dissipation - تجمع چسبناکCFD - دینامیک سیالاتComputational fluid dynamics - دینامیک سیالات محاسباتیecho time - زمان اکوRepetition time - زمان تکرارright pulmonary artery - شریان ریوی راستLeft pulmonary artery - شریان ریوی چپfontan - فونتنInferior vena cava - پایین پنجه گاوvelocity encoding - کدگذاری سریع
موضوعات مرتبط
مهندسی و علوم پایه
سایر رشته های مهندسی
مهندسی پزشکی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Viscous dissipation inside Fontan circulation, a parameter associated with the exercise intolerance of Fontan patients, can be derived from computational fluid dynamics (CFD) or 4D flow MRI velocities. However, the impact of spatial resolution and measurement noise on the estimation of viscous dissipation is unclear. Our aim was to evaluate the influence of these parameters on viscous dissipation calculation. Six Fontan patients underwent whole heart 4D flow MRI. Subject-specific CFD simulations were performed. The CFD velocities were down-sampled to isotropic spatial resolutions of 0.5 mm, 1 mm, 2 mm and to MRI resolution. Viscous dissipation was compared between (1) high resolution CFD velocities, (2) CFD velocities down-sampled to MRI resolution, (3) down-sampled CFD velocities with MRI mimicked noise levels, and (4) in-vivo 4D flow MRI velocities. Relative viscous dissipation between subjects was also calculated. 4D flow MRI velocities (15.6±3.8 cm/s) were higher, although not significantly different than CFD velocities (13.8±4.7 cm/s, p=0.16), down-sampled CFD velocities (12.3±4.4 cm/s, p=0.06) and the down-sampled CFD velocities with noise (13.2±4.2 cm/s, p=0.06). CFD-based viscous dissipation (0.81±0.55 mW) was significantly higher than those based on down-sampled CFD (0.25±0.19 mW, p=0.03), down-sampled CFD with noise (0.49±0.26 mW, p=0.03) and 4D flow MRI (0.56±0.28 mW, p=0.06). Nevertheless, relative viscous dissipation between different subjects was maintained irrespective of resolution and noise, suggesting that comparison of viscous dissipation between patients is still possible.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Biomechanics - Volume 48, Issue 12, 18 September 2015, Pages 2984-2989
Journal: Journal of Biomechanics - Volume 48, Issue 12, 18 September 2015, Pages 2984-2989
نویسندگان
Merih Cibis, Kelly Jarvis, Michael Markl, Michael Rose, Cynthia Rigsby, Alex J. Barker, Jolanda J. Wentzel,