کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10432092 | 910236 | 2014 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Numerical investigations of the haemodynamic changes associated with stent malapposition in an idealised coronary artery
ترجمه فارسی عنوان
بررسی های عددی تغییرات همودینامیکی مرتبط با ناپایداری استنت در یک آرتریت عروق کرونر ایده آل
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کلمات کلیدی
اختلال استنت، استنت کرونر، آترواسکلروز، در سیلیکا، استرس برشی دیوار،
موضوعات مرتبط
مهندسی و علوم پایه
سایر رشته های مهندسی
مهندسی پزشکی
چکیده انگلیسی
The deployment of a coronary stent near complex lesions can sometimes lead to incomplete stent apposition (ISA), an undesirable side effect of coronary stent implantation. Three-dimensional computational fluid dynamics (CFD) calculations are performed on simplified stent models (with either square or circular cross-section struts) inside an idealised coronary artery to analyse the effect of different levels of ISA to the change in haemodynamics inside the artery. The clinical significance of ISA is reported using haemodynamic metrics like wall shear stress (WSS) and wall shear stress gradient (WSSG). A coronary stent with square cross-sectional strut shows different levels of reverse flow for malapposition distance (MD) between 0Â mm and 0.12Â mm. Chaotic blood flow is usually observed at late diastole and early systole for MD=0Â mm and 0.12Â mm but are suppressed for MD=0.06Â mm. The struts with circular cross section delay the flow chaotic process as compared to square cross-sectional struts at the same MD and also reduce the level of fluctuations found in the flow field. However, further increase in MD can lead to chaotic flow not only at late diastole and early systole, but it also leads to chaotic flow at the end of systole. In all cases, WSS increases above the threshold value (0.5Â Pa) as MD increases due to the diminishing reverse flow near the artery wall. Increasing MD also results in an elevated WSSG as flow becomes more chaotic, except for square struts at MD=0.06Â mm.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Biomechanics - Volume 47, Issue 12, 22 September 2014, Pages 2843-2851
Journal: Journal of Biomechanics - Volume 47, Issue 12, 22 September 2014, Pages 2843-2851
نویسندگان
Eric K.W. Poon, Peter Barlis, Stephen Moore, Wei-Han Pan, Yun Liu, Yufei Ye, Yuan Xue, Shuang J. Zhu, Andrew S.H. Ooi,