کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10432592 | 910253 | 2013 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Mechanical analysis of ovine and pediatric pulmonary artery for heart valve stent design
ترجمه فارسی عنوان
تجزیه و تحلیل مکانیکی عروق ریوی در کودکان و کودکان برای طراحی دریچه قلب دریچه
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
شریان ریوی، جایگزینی سوپاپ قلب آزمون کششی دو طرفه، طراحی استنت کودکان، مدل سازی پایه،
موضوعات مرتبط
مهندسی و علوم پایه
سایر رشته های مهندسی
مهندسی پزشکی
چکیده انگلیسی
Transcatheter heart valve replacement is an attractive and promising technique for congenital as well as acquired heart valve disease. In this procedure, the replacement valve is mounted in a stent that is expanded at the aimed valve position and fixated by clamping. However, for this technique to be appropriate for pediatric patients, the material properties of the host tissue need to be determined to design stents that can be optimized for this particular application. In this study we performed equibiaxial tensile tests on four adult ovine pulmonary artery walls and compared the outcomes with one pediatric pulmonary artery. Results show that the pediatric pulmonary artery was significantly thinner (1.06±0.36 mm (mean±SD)) than ovine tissue (2.85±0.40 mm), considerably stiffer for strain values that exceed the physiological conditions (beyond 50% strain in the circumferential and 60% in the longitudinal direction), more anisotropic (with a significant difference in stiffness between the longitudinal and circumferential directions beyond 60% strain) and presented stronger non-linear stress-strain behavior at equivalent strains (beyond 26% strain) compared to ovine tissue. These discrepancies suggest that stents validated and optimized using the ovine pre-clinical model might not perform satisfactorily in pediatric patients. The material parameters derived from this study may be used to develop stent designs for both applications using computational models.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Biomechanics - Volume 46, Issue 12, 9 August 2013, Pages 2075-2081
Journal: Journal of Biomechanics - Volume 46, Issue 12, 9 August 2013, Pages 2075-2081
نویسندگان
M.S. Cabrera, C.W.J. Oomens, C.V.C. Bouten, A.J.J.C. Bogers, S.P. Hoerstrup, F.P.T. Baaijens,