کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10433661 | 910370 | 2005 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Length-dependent [Ca2+] sensitivity adds stiffness to muscle
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موضوعات مرتبط
مهندسی و علوم پایه
سایر رشته های مهندسی
مهندسی پزشکی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Length-dependent [Ca2+] sensitivity adds stiffness to muscle Length-dependent [Ca2+] sensitivity adds stiffness to muscle](/preview/png/10433661.png)
چکیده انگلیسی
It is well documented that muscle fibers become more sensitive for [Ca2+] with increasing sarcomere length. In mechanical terms this length-dependent [Ca2+] sensitivity (LDCS) adds to the stiffness of muscle fibers, because muscle force, normalized for the force-length relationship at maximal stimulation, increases with contractile element (CE) length. Although LDCS is well-documented in the physiological literature, it is ignored in most motor control studies. The aim of the present study was to investigate the importance of LDCS as a contributor to the stiffness of a muscle. Comparison of experimental data with predictions derived from the model of activation dynamics proposed by Hatze (Myocybernetic Control Models of Skeletal Muscle, University of South Africa, Pretoria, 1981, pp. 31-42) indicated that this model captures the main characteristics of LDCS well. It was shown that LDCS accounts for the experimentally observed shifts in optimum length at sub-maximal stimulation levels. Furthermore, it was shown that in conditions with low-to-medium muscle stimulation, the contribution of LDCS to the total amount of stiffness provided by the muscle is substantial. It was concluded that LDCS is an important muscle property and should be taken into account in studies concerning motor control.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Biomechanics - Volume 38, Issue 9, September 2005, Pages 1816-1821
Journal: Journal of Biomechanics - Volume 38, Issue 9, September 2005, Pages 1816-1821
نویسندگان
Dinant A. Kistemaker, Arthur (Knoek) J. Van Soest, Maarten F. Bobbert,