The role of CBT in explicit memory bias in bipolar I patients

► The “neurotoxic” impact of past depressive episodes on memory. ► Cognitive-Behavioural Therapy of bipolar disorder in challenging memory biases. ► Controlled study (n = 73) with multiple baseline and 6-months follow-up. ► Significant effect confirmed for the negative impact of past depressive episodes on memory. ► Therapy found to improve mood and memory biases for negative words.