Possible key intermediates in arsenic biochemistry: Synthesis and identification by liquid chromatography electrospray ionization mass spectrometry and high resolution mass spectrometry

They also offer an explanation for the reason why arsenobetaine, and tetramethylarsonium are loosely bound to biotic tissues. Four arsenic species new to science, to the best of our knowledge, and a number of known arsenic compounds were synthesized in this work, identified by HPLC-ESI-MSn and FTICR-ESI-MS, and suggestions regarding their mechanisms of synthesis were advanced. These results provide a framework for arsenic biochemistry which may explain the origin of a significant part of arsenic known metabolites.