کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10566851 | 972357 | 2005 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Effect of the shape of human erythrocytes on the evaluation of the passive electrical properties of the cell membrane
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
الکتروشیمی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Effect of the shape of human erythrocytes on the evaluation of the passive electrical properties of the cell membrane Effect of the shape of human erythrocytes on the evaluation of the passive electrical properties of the cell membrane](/preview/png/10566851.png)
چکیده انگلیسی
The possible influence of the cell shape on the derivation of the passive electrical parameters of a biological cell membrane is discussed in light of two different models which describe the cell as a shelled ellipsoidal particle and as a biconcave disk obtained by the revolution of the Cassini oval, respectively. Whereas within the first model, the Laplace equation can be solved analytically, in the second one a numerical algorithm based on the boundary element method has been employed. We have compared the results obtained by these two different models in the case of normal human erythrocyte cell membrane, using radiowave dielectric spectroscopy measurements. Our findings show that, although in principle the cell shape might deeply affect the evaluation of the passive electrical parameters of the cell membrane, in the case of the erythrocyte shape modelled by the Cassini curve, only small deviations are evidenced in comparison to the values derived, as usually done in the dielectric spectroscopy of biological cell suspensions, from an ellipsoidal model analysis. This result gives further support to the reliability of the data reported in the literature based on an ellipsoidal shape erythrocyte model.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioelectrochemistry - Volume 65, Issue 2, February 2005, Pages 163-169
Journal: Bioelectrochemistry - Volume 65, Issue 2, February 2005, Pages 163-169
نویسندگان
A. Di Biasio, C. Cametti,