کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10567329 | 972641 | 2005 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Design, preparation and testing of suitable probe-receptors for RNA biosensing
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
الکتروشیمی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Design, preparation and testing of suitable probe-receptors for RNA biosensing Design, preparation and testing of suitable probe-receptors for RNA biosensing](/preview/png/10567329.png)
چکیده انگلیسی
Automated chemical synthesis of selected probes was performed and the oligonucleotides produced were covalently conjugated to the sensing surface of a quartz microbalance. The microgravimetric sensor was tested in a flow chamber by measuring the variation of resonance frequency due to the binding of synthetic target substrates. Specific dose dependent binding was observed. Furthermore, the binding of a transcribed full-length mRNA substrate was successfully monitored under similar conditions.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioelectrochemistry - Volume 67, Issue 2, October 2005, Pages 171-179
Journal: Bioelectrochemistry - Volume 67, Issue 2, October 2005, Pages 171-179
نویسندگان
L. Tedeschi, A. Mercatanti, C. Domenici, L. Citti,