کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10706798 | 1023506 | 2005 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
In vitro assessment of biocompatibility of biomaterials by using fluorescent yeast biosensor
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
فیزیک و نجوم
فیزیک ماده چگال
پیش نمایش صفحه اول مقاله
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چکیده انگلیسی
For genotoxicity test, a multicopy plasmid bearing a RAD54 promoter fused to GFP was used as a sensing part of yeast cells. The monomers of dental resin (HEMA, TEGDMA and UDMA) were tested for their mutagenicity. Among the monomers, TEGDMA exhibited the increase of fluorescence. This result indicates that the test with yeast may produce the scores of genotoxicity closer to those obtained with mammalian cells rather than bacteria. In conclusion, this study showed the usefulness of yeast cells for in vitro biocompatibility test of biomaterials.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Current Applied Physics - Volume 5, Issue 5, July 2005, Pages 444-448
Journal: Current Applied Physics - Volume 5, Issue 5, July 2005, Pages 444-448
نویسندگان
Hyeong-Cheol Yang, Bum-Soon Lim, Yong-keun Lee,