کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10706822 | 1023506 | 2005 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis and characterization of Pluronic® grafted chitosan copolymer as a novel injectable biomaterial
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
فیزیک و نجوم
فیزیک ماده چگال
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Water-soluble thermosensitive chitosan copolymers were prepared by coupling Pluronic® onto chitosan using 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide (EDC) and N-hydroxysuccinimide (NHS) as coupling agents. The physicochemical properties of the resulting copolymers were characterized and they formed thermally reversible hydrogels, which exhibit a lower critical solution temperature (LCST) at 34 °C in aqueous solutions. As a result, chitosan copolymers attest to the usefulness as an injectable material for cell and drug delivery because of their thermally reversible property.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Current Applied Physics - Volume 5, Issue 5, July 2005, Pages 485-488
Journal: Current Applied Physics - Volume 5, Issue 5, July 2005, Pages 485-488
نویسندگان
Ho Jin Chung, Dong Hyun Go, Jin Woo Bae, In Kwon Jung, Joon Woo Lee, Ki Dong Park,