کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10712399 1025183 2016 27 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Age-effects in white matter using associated diffusion tensor imaging and magnetization transfer ratio during late childhood and early adolescence
ترجمه فارسی عنوان
اثرات سن در مواد سفید با استفاده از تانسور انتشار تونر و نسبت انتقال مغناطیسی در دوران کودکی و نوجوانی در اوایل
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه فیزیک و نجوم فیزیک ماده چگال
چکیده انگلیسی
In the last decade, several studies have described the typical brain white matter maturation in children and adolescents. Diffusion tensor imaging (DTI) is the most frequent MRI technique used to investigate the structural changes across development. However, few previous studies have used the magnetization transfer ratio (MTR), which gives a closer measure of myelin content. Here, we employed both techniques for the same sample of 176 typically developing children from 7 to 14 years of age. We investigated the associations between DTI parameters and MTR measure, to assess the myelination in the brain in development. Secondly, we investigated age-effects on DTI parameters (fractional anisotropy, axial, radial and mean diffusivities) and MTR. No significant correlations between MTR and DTI parameters were observed. In addition, a significant age-effect was detected for DTI data but was not visible for MTR data. Thereby, changes in white matter at this age might be primarily correlated with microstructural changes.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Magnetic Resonance Imaging - Volume 34, Issue 4, May 2016, Pages 529-534
نویسندگان
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