Assessment and management of Clostridium difficile

Clostridium difficile (C.difficile) infection has become more common in the healthcare environment over recent years. The number of cases has increased dramatically and has been responsible for severe morbidity and mortality. Assessment and management of patients with confirmed or suspected C.difficile associated diarrhoea is discussed and summarized as a guide for junior doctors in the clinical environment. As with all infective disease, the most important factor remains its prevention. Decline in rates will only come by increasing awareness of the condition, educating healthcare professionals on appropriate antibiotic prescription and improving on good hand hygiene in the healthcare environment.