MicroRNAs linking inflamm-aging, cellular senescence and cancer

- MicroRNAs can be a link between inflamm-aging, cellular senescence and cancer.
- NF-κB activation is at the crossroad between inflamma-aging, senescence and cancer.
- MiR-21, -126 and -146a target NF-κB pathway.
- MiR-21, -126 and -146a are deregulated in inflamma-aging, senescence and cancer.
- MiR-21 is deregulated in centenarians, individuals escaped from the age-related diseases.