The effect of fasting on indicators of muscle damage

► We tested effects of fasting on exercise-induced muscle damage in humans. ► Daily 8-hour fasts were compared to a controlled meal within 4-5 h of visit. ► Indicators of damage were collected before and across five days after exercise. ► The fasts did not robustly protect against exercise-induced muscle damage. ► However, NO was higher and TNFa was lower in the fasting group across time.