کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10821764 | 1061514 | 2011 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Effects of cadmium on carbohydrate and protein metabolisms in the freshwater crab Sinopotamon yangtsekiense
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موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شیمی
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چکیده انگلیسی
The physiological impact of Cd2+ on Sinopotamon yangtsekiense was evaluated through changes of selected parameters considered as key elements of carbohydrate and protein metabolisms. Crab were exposed to 0.725, 1.45, 2.9 mg·Lâ 1 Cd2+ for 7, 14 and 21 days. A time- and/or concentration- dependent decrease in muscle glycogen and increase in LDH activity suggested that glycolysis was accelerated during the treatments. Increased protease activity, lowering of FAA and the initially increased and subsequently decreased aminotransferase activities suggest an enhanced protein mobilization during early Cd2+ exposure followed by a metabolic impairment during late exposure. Decreased hemolymph glucose level was observed in the crabs treated with 2.9 mg·Lâ 1 Cd2+ for 21 d, suggesting an impaired gluconeogenesis. Ammonia level barely changed during the 14 d Cd2+ exposure most likely due to the increased urea and glutamine production; After 1.45 and 2.9 mg·Lâ 1 Cd2+ treatment for 21 d, ammonia was observed increased followed by an exclusive increase in glutamine. Taken together, our results indicate that carbohydrate and protein are mobilized to a varying degree as a compensatory metabolism to response to the energy stress during acute Cd2+ exposure. As the time lapsed, some symptoms on metabolism obstacle reflect the toxic effect of sublethal Cd2+.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology - Volume 154, Issue 3, September 2011, Pages 268-274
Journal: Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology - Volume 154, Issue 3, September 2011, Pages 268-274
نویسندگان
Ruijing Xuan, Lan Wang, Min Sun, Guorui Ren, Meiling Jiang,